Protein Alignment CG8641 and Rasd2

DIOPT Version :9

• Sequence 1: NP_001261494.1
• Gene: CG8641 / 38771
• FlyBaseID: FBgn0035733
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: NP_598252.1
• Gene: Rasd2 / 171099
• RGDID: 628594
• Length: 266
• Species: Rattus norvegicus
• Alignment Length: 270
• Identity: 127/270 - (47%)
• Similarity: 175/270 - (64%)
• Gaps: 28/270 - (10%)

  Fly   156 CDDSLPSAKNCYRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQLDILD 220
            |..::| |||.||:|:||:||.||||||:|||..|||:.||||||:||||:|.|..:::||||||
  Rat    10 CTLNVP-AKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIHGDMYQLDILD 73

  Fly   221 TSGYHPFPAMRRLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGSGFKKKSLPKI 285
            |||.||||||||||.||||:||||||:||||||:||.||::.|||.|....|     |.|...::
  Rat    74 TSGNHPFPAMRRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVKSCLKN-----KTKEAAEL 133

  Fly   286 PMILAGNKCDRD--FKTVQVDEVMGYIAGQDNCCTFVECSARQNYRIDDLFHSLFTVSNLPLEMT 348
            ||::.|||.|..  .:.|...|....::|.:||..| |.||::|..::::|:.||:::.||.||:
  Rat   134 PMVICGNKNDHSELCRQVPAMEAELLVSGDENCAYF-EVSAKKNTNVNEMFYVLFSMAKLPHEMS 197

  Fly   349 PNHHRRLVSVFG---APSPLPPHGSAVGGTKKNALSIKRRFSDACGVVTPNARRPSIRTDLNLMR 410
            |..|.::...:|   .|.|.....:.|.|              |.|:|:|.|||||:.:||..::
  Rat   198 PALHHKISVQYGDAFHPRPFCMRRTKVAG--------------AYGMVSPFARRPSVNSDLKYIK 248

  Fly   411 SKTMALNEGE 420
            :|  .|.||:
  Rat   249 AK--VLREGQ 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8641	NP_001261494.1	Rhes_like	167..434	CDD:133343	122/259 (47%)
		RAS	167..338	CDD:214541	94/172 (55%)
Rasd2	NP_598252.1	Rhes_like	20..266	CDD:133343	122/259 (47%)
		Effector region	48..56		6/7 (86%)
		Interaction with GNB1, GNB2 and GNB3. /evidence=ECO:0000250	189..235		15/59 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	190	1.000	Domainoid score	I3176
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I3324
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1398885at2759
OrthoFinder	1	1.000	-	-		FOG0005519
OrthoInspector	1	1.000	-	-		otm44460
orthoMCL	1	0.900	-	-		OOG6_107719
Panther	1	1.100	-	-	O	PTHR46149
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3937
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830