Protein Alignment Galphai and GPA1

DIOPT Version :10

• Sequence 1: NP_477502.1
• Gene: Galphai / 38765
• FlyBaseID: FBgn0001104
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_011868.1
• Gene: GPA1 / 856394
• SGDID: S000001047
• Length: 472
• Species: Saccharomyces cerevisiae
• Alignment Length: 473
• Identity: 172/473 - (36%)
• Similarity: 247/473 - (52%)
• Gaps: 121/473 - (25%)

  Fly     1 MGCAVST---ARDKEAIERSKN----IDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIH 58
            |||.|||   ..:.:...::|.    |:::|:.|.:|..:|:||||||||||||||::||:|::|
Yeast     1 MGCTVSTQTIGDESDPFLQNKRANDVIEQSLQLEKQRDKNEIKLLLLGAGESGKSTVLKQLKLLH 65

  Fly    59 DTGYSQEECEEYRRVVFSNTVQSLMVII------------------------------------- 86
            ..|:|.:|..:|.:|::::.:||:.::|
Yeast    66 QGGFSHQERLQYAQVIWADAIQSMKILIIQARKLGIQLDCDDPINNKDLFACKRILLKAKALDYI 130

  Fly    87 ----------------------------RAMGRLKIEF-----------------------ADPS 100
                                        ::.||.|..|                       .|..
Yeast   131 NASVAGGSDFLNDYVLKYSERYETRRRVQSTGRAKAAFDEDGNISNVKSDTDRDAETVTQNEDAD 195

  Fly   101 RTDIAR----------------QFFTHASAAD------EGILLPEIVLLMKKLW-ADGGVQQSFA 142
            |.:.:|                |.|...::.:      ..::..:|...:|:|| .|.|::|.||
Yeast   196 RNNSSRINLQDICKDLNQEGDDQMFVRKTSREIQGQNRRNLIHEDIAKAIKQLWNNDKGIKQCFA 260

  Fly   143 RSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQLHFKLFDVGGQRS 207
            ||.|:||..||.||.:::::.|.|||:.|.:|:|:.|:|||||.||.|:.....||:.|.|||||
Yeast   261 RSNEFQLEGSAAYYFDNIEKFASPNYVCTDEDILKGRIKTTGITETEFNIGSSKFKVLDAGGQRS 325

  Fly   208 ERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSKWFVETSIILFLNKK 272
            |||||||||||:||::|.:|:|.||.:|.|||.:|||.||:.|||::.|||||.:|..||||||.
Yeast   326 ERKKWIHCFEGITAVLFVLAMSEYDQMLFEDERVNRMHESIMLFDTLLNSKWFKDTPFILFLNKI 390

  Fly   273 DLFEEKIKRSPLTICFPEYTG-TNTFEEAANYIRMKFENLNKRKDQKEIYTHLTCATDTNNVKFV 336
            ||||||:|..|:...||:|.| ....|....|....|.:||  |..|.||...||||||..:|||
Yeast   391 DLFEEKVKSMPIRKYFPDYQGRVGDAEAGLKYFEKIFLSLN--KTNKPIYVKRTCATDTQTMKFV 453

  Fly   337 FDAVTDVIIKNNLKQIGL 354
            ..||||:||:.|||:||:
Yeast   454 LSAVTDLIIQQNLKKIGI 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	155/425 (36%)
GPA1	NP_011868.1	G-alpha	42..466	CDD:206639	155/425 (36%)