Protein Alignment Galphai and Gnao1

DIOPT Version :10

• Sequence 1: NP_477502.1
• Gene: Galphai / 38765
• FlyBaseID: FBgn0001104
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_059023.1
• Gene: Gnao1 / 50664
• RGDID: 628732
• Length: 354
• Species: Rattus norvegicus
• Alignment Length: 363
• Identity: 231/363 - (63%)
• Similarity: 283/363 - (77%)
• Gaps: 17/363 - (4%)

  Fly     1 MGCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQE 65
            |||.:| |.::.|:||||.|::.|:.:|..||.:||||||||||||||||||||||||:.|:|.|
  Rat     1 MGCTLS-AEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGE 64

  Fly    66 ECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTD--------IARQFFTHASAADEGILLP 122
            :.::|:.||:|||:|||..|:|||..|.:|:.|..|..        ::|...|...:|
  Rat    65 DVKQYKPVVYSNTIQSLAAIVRAMDTLGVEYGDKERKADSKMVCDVVSRMEDTEPFSA------- 122

  Fly   123 EIVLLMKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIE 187
            |::..|.:||.|.|:|:.|.|||||||||||.|||:|||||...:|.||:||:||||||||||:|
  Rat   123 ELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVE 187

  Fly   188 THFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFD 252
            |||:.|.|||:|||||||||||||||||||.||||||||||||||.||.|||..|||.|||.|||
  Rat   188 THFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFD 252

  Fly   253 SICNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAANYIRMKFENLNKRKDQ 317
            ||||:|:|::|||||||||||||.||||:||||||||||.|:||:|:||.||:.:||:.| |...
  Rat   253 SICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYPGSNTYEDAAAYIQTQFESKN-RSPN 316

  Fly   318 KEIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGLF 355
            ||||.|:||||||||::.|||||||:||.|||:..||:
  Rat   317 KEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	212/321 (66%)
Gnao1	NP_059023.1	G-alpha	34..348	CDD:206639	212/321 (66%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	35..48		12/12 (100%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	174..182		6/7 (86%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	197..206		7/8 (88%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	266..273		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	324..329		4/4 (100%)