Protein Alignment Galphai and Gna13

DIOPT Version :10

• Sequence 1: NP_477502.1
• Gene: Galphai / 38765
• FlyBaseID: FBgn0001104
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_001013137.1
• Gene: Gna13 / 303634
• RGDID: 1310221
• Length: 377
• Species: Rattus norvegicus
• Alignment Length: 361
• Identity: 148/361 - (40%)
• Similarity: 216/361 - (59%)
• Gaps: 9/361 - (2%)

  Fly     2 GCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQEE 66
            || |.|..:.|...:||.||:.|..|.......||:||||||||||||.:|||:|||...:.|..
  Rat    17 GC-VLTNGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRA 80

  Fly    67 CEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRT---DIARQFFTHASAADEGILLPEIVL-- 126
            .||:|..::||.::.:.|::.|..:|.|.:.|....   |....|.|.|..|.:|::...:.|
  Rat    81 REEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQVHGDKLMAFDTRAPMAAQGMVETRVFLQY 145

  Fly   127 --LMKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETH 189
              .::.||.|.|:|.::.|.||:||.:|..|:|::||::..|:|||:|||:|..|..|.||.|..
  Rat   146 LPAIRALWDDSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHEYD 210

  Fly   190 FSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSI 254
            |..|.:.||:.||||||||||:|..||:.||:|:|.|:.|.:|.||.||...||:.|||.:|::|
  Rat   211 FEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETI 275

  Fly   255 CNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTG-TNTFEEAANYIRMKFENLNKRKDQK 318
            .|::.|...||||||||.||.|||::...:...|.|:.| .:...:...::...|....:.:.|:
  Rat   276 VNNRVFSNVSIILFLNKTDLLEEKVQVVSIKDYFLEFEGDPHCLRDVQKFLVECFRGKRRDQQQR 340

  Fly   319 EIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
            .:|.|.|.|.:|.|::.||..|.|.|:.:||||:.|
  Rat   341 PLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLML 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	132/321 (41%)
Gna13	NP_001013137.1	G_alpha	29..375	CDD:214595	142/345 (41%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	50..63		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	195..203		3/7 (43%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	218..227		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	287..294		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	347..352		2/4 (50%)