DRSC/TRiP Functional Genomics Resources

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Protein Alignment Galphai and Gnas

DIOPT Version :10

Sequence 1:NP_477502.1 Gene:Galphai / 38765 FlyBaseID:FBgn0001104 Length:355 Species:Drosophila melanogaster
Sequence 2:XP_063139191.1 Gene:Gnas / 24896 RGDID:2716 Length:1145 Species:Rattus norvegicus


Alignment Length:404 Identity:157/404 - (38%)
Similarity:215/404 - (53%) Gaps:76/404 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 KEAIE----------RSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQE 65
            |||:|          |||.||:.|..|........:||||||||||||||||||:|:|..|::.|
  Rat   757 KEAMEMREQKRADKKRSKLIDKQLEEEKMDYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGE 821

  Fly    66 ECEEYRRVVFSNT----------------VQSLMVIIRAMGRL--KIEFADPSRT---------- 102
            ..||..:...||:                .:::..|:.||..|  .:|.|:|...          
  Rat   822 GGEEDPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVM 886

  Fly   103 -----DIARQFFTHASAADEGILLPEIVLLMKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDR 162
                 |...:|:.||                |.||.|.||:..:.||.||||.|.|.|:|:.:|.
  Rat   887 NVPNFDFPPEFYEHA----------------KALWEDEGVRACYERSNEYQLIDCAQYFLDKIDV 935

  Fly   163 IAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVA 227
            |.|.:|:|:.||:||.||.|:||.||.|...:::|.:|||||||.||:|||.||..||||||.||
  Rat   936 IKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVA 1000

  Fly   228 LSGYDLVLAEDEEMNRMIESLKLFDSICNSKWFVETSIILFLNKKDLFEEKI--KRSPLTICFPE 290
            .|.|::|:.||.:.||:.|:|.||.||.|::|....|:||||||:||..||:  .:|.:...|||
  Rat  1001 SSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPE 1065

  Fly   291 YTGTNTFEEA------------ANY-IRMKFENLNKRK--DQKEIYTHLTCATDTNNVKFVFDAV 340
            :....|.|:|            |.| ||.:|..::...  .:...|.|.|||.||.|::.||:..
  Rat  1066 FARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDC 1130

  Fly   341 TDVIIKNNLKQIGL 354
            .|:|.:.:|:|..|
  Rat  1131 RDIIQRMHLRQYEL 1144

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GalphaiNP_477502.1 G-alpha 35..349 CDD:206639 143/363 (39%)
GnasXP_063139191.1 None

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