Protein Alignment Galphai and Gnao1

DIOPT Version :10

• Sequence 1: NP_477502.1
• Gene: Galphai / 38765
• FlyBaseID: FBgn0001104
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_034438.1
• Gene: Gnao1 / 14681
• MGIID: 95775
• Length: 354
• Species: Mus musculus
• Alignment Length: 363
• Identity: 233/363 - (64%)
• Similarity: 285/363 - (78%)
• Gaps: 17/363 - (4%)

  Fly     1 MGCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQE 65
            |||.:| |.::.|:||||.|::.|:.:|..||.:||||||||||||||||||||||||:.|:|.|
Mouse     1 MGCTLS-AEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGE 64

  Fly    66 ECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSR-TD-------IARQFFTHASAADEGILLP 122
            :.::|:.||:|||:|||..|:|||..|.:|:.|..| ||       ::|...|...:|
Mouse    65 DVKQYKPVVYSNTIQSLAAIVRAMDTLGVEYGDKERKTDSKMVCDVVSRMEDTEPFSA------- 122

  Fly   123 EIVLLMKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIE 187
            |::..|.:||.|.|:|:.|.|||||||||||.|||:|||||...:|.||:||:||||||||||:|
Mouse   123 ELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAGDYQPTEQDILRTRVKTTGIVE 187

  Fly   188 THFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFD 252
            |||:.|.|||:|||||||||||||||||||.||||||||||||||.||.|||..|||.|||.|||
Mouse   188 THFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFD 252

  Fly   253 SICNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAANYIRMKFENLNKRKDQ 317
            ||||:|:|::|||||||||||||.||||:||||||||||.|:||:|:||.||:.:||:.| |...
Mouse   253 SICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYPGSNTYEDAAAYIQTQFESKN-RSPN 316

  Fly   318 KEIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGLF 355
            ||||.|:||||||||::.|||||||:||.|||:..||:
Mouse   317 KEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	214/321 (67%)
Gnao1	NP_034438.1	G-alpha	34..348	CDD:206639	214/321 (67%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	35..48		12/12 (100%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	174..182		6/7 (86%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	197..206		7/8 (88%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	266..273		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	324..329		4/4 (100%)