Protein Alignment Galphai and Gna11

DIOPT Version :10

• Sequence 1: NP_477502.1
• Gene: Galphai / 38765
• FlyBaseID: FBgn0001104
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_034431.1
• Gene: Gna11 / 14672
• MGIID: 95766
• Length: 359
• Species: Mus musculus
• Alignment Length: 367
• Identity: 172/367 - (46%)
• Similarity: 226/367 - (61%)
• Gaps: 28/367 - (7%)

  Fly     1 MGCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQE 65
            |.|.:|. ..||:...:..|::.||.:...|..|:||||||.|||||||.:|||:|||..|||:|
Mouse     7 MACCLSD-EVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEE 70

  Fly    66 ECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHASAADEGILLPEI------ 124
            :...:.::|:.|...::..::|||..|||             .:.:.......:|:.|:
Mouse    71 DKRGFTKLVYQNIFTAMQAMVRAMETLKI-------------LYKYEQNKANALLIREVDVEKVT 122

  Fly   125 ------VLLMKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTT 183
                  |..:|.||:|.|||:.:.|.||:||:|||.|||..:||||...|:||||||||.||.||
Mouse   123 TFEHQYVNAIKTLWSDPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTT 187

  Fly   184 GIIETHFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESL 248
            ||||..|..:.:.|::.|||||||||:|||||||.||:|:|.||||.||.||.|.:..|||.||.
Mouse   188 GIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESK 252

  Fly   249 KLFDSICNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAA-NYIRMKFENLN 312
            .||.:|....||..:|:|||||||||.|:||..|.|...|||:.|.....:|| .:|...|.:||
Mouse   253 ALFRTIITYPWFQNSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFVDLN 317

  Fly   313 KRKDQKEIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
            ...| |.||:|.||||||.|::|||.||.|.|::.|||:..|
Mouse   318 PDSD-KIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	158/326 (48%)
Gna11	NP_034431.1	G-alpha	40..353	CDD:206639	158/326 (48%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	41..54		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	178..186		6/7 (86%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	201..210		5/8 (63%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	270..277		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	329..334		4/4 (100%)