Protein Alignment CG9953 and Prss16

DIOPT Version :10

• Sequence 1: NP_648067.2
• Gene: CG9953 / 38763
• FlyBaseID: FBgn0035726
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_062302.1
• Gene: Prss16 / 54373
• MGIID: 1859181
• Length: 509
• Species: Mus musculus
• Alignment Length: 506
• Identity: 179/506 - (35%)
• Similarity: 242/506 - (47%)
• Gaps: 46/506 - (9%)

  Fly    13 VGLLLL----GLLAPISGMGFRRGR-----------LTKGF-LGE-PSKIPTLQRSLHSEDLWFE 60
            :|.|||    ||..|  .:..||.|           |..|| ||. |..:|        :..|.|
Mouse     8 LGFLLLVSLWGLSTP--ALLLRRLREHIQKFQESSSLHPGFGLGHGPGAVP--------KQGWLE 62

  Fly    61 QRLDHFKSSDKRTWQQRYFVNADFYRNDSSAPVFLMIGGEGEASAKWMREGAWVHYAEHFGALCL 125
            |.||.|.:||:||:.|||:|| |.:|.....||||.|||||......:..|.....|..:|||.:
Mouse    63 QPLDPFNASDRRTFLQRYWVN-DQHRTGQDVPVFLHIGGEGSLGPGSVMAGHPAALAPAWGALVI 126

  Fly   126 QLEHRFYGKSHPTADLSTENLHYLSSEQALEDLASFVTAMKVKFNLGDGQKWIAFGGSYPGSLAA 190
            .|||||||.|.|...|....|.||||..||.|:||...|:....|:.....||.|||||.||||.
Mouse   127 SLEHRFYGLSMPAGGLDLALLRYLSSRHALADVASARQALSGLLNVSSSSPWICFGGSYAGSLAT 191

  Fly   191 WAREKYPELIYGSISSSGPLLAEVDFKEYFEVVKASLAAY----KPECVDAVTRSFAQVEILLK- 250
            |||.|:|.|::.:::||.||.|.|||..|.:||..||...    ..||:.|.:.:|.:||.||:
Mouse   192 WARLKFPHLVFAAVASSAPLSAVVDFSAYNQVVARSLTQVAIGGSLECLAAASTAFTEVERLLRA 256

  Fly   251 HMIGQRSLDEKFKTCTPIKDSIENDLDMANFFENLAGNFAGVVQYNKDNSPHATITIDDICDVML 315
            ....|..|.|:...|..: |..|:..::....:.|.|   |.|||  |....|.:::..:|.::|
Mouse   257 GPAAQAVLREELGACGSL-DLTEDQAELLGALQALVG---GTVQY--DGQAGAPLSVRQLCGLLL 315

  Fly   316 ----NTTAGPPVTRLGLVNDMLLKESNTTCLDYKYDKMVADMKNVSWDSETAKGMRQWTYQTCHE 376
                |.:...|...|.....::|:.....||.:...:.||.:.|.. ...:..|.|||.||||.|
Mouse   316 GKWGNRSRSTPYLGLRRAVQIVLRSMGQKCLSFSRAETVAQLSNTE-PQVSGVGDRQWLYQTCTE 379

  Fly   377 FGFYQTSDNPADTFGDRFGVDFFIRQCMDVFSKNMNAKFLKLVVSATNDNYGALKPKTTNVLYVH 441
            ||||.|.:.....|.....:.|.:..|..||  .::...:...|:.||..||...|..|.||:|:
Mouse   380 FGFYVTCEGLQCPFSQLPALPFQLELCEQVF--GLSPASVAQAVAQTNSYYGGQSPGATQVLFVN 442

  Fly   442 GSIDPWHALGLVKSTNAALPTIYIEGTAHCANMYEPVKTDPPQLVAARNKI 492
            |..||||.|.:.:....:.|.:.|...:||.:|.....:|.|.|...|.||
Mouse   443 GDTDPWHVLSVTQDLGLSEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKI 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9953	NP_648067.2	Peptidase_S28	61..492	CDD:310284	158/439 (36%)
Prss16	NP_062302.1	Peptidase_S28	63..493	CDD:310284	158/439 (36%)