Protein Alignment CG9953 and PRSS16

DIOPT Version :10

• Sequence 1: NP_648067.2
• Gene: CG9953 / 38763
• FlyBaseID: FBgn0035726
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_005856.1
• Gene: PRSS16 / 10279
• HGNCID: 9480
• Length: 514
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 180/512 - (35%)
• Similarity: 250/512 - (48%)
• Gaps: 50/512 - (9%)

  Fly    13 VGLLLL----GLLAPISGMGFRRGRLTKGFLGEPSKIPTLQRSLHSEDL---------------W 58
            :|.|||    |||||.|.:  ||       |||  .|...|.| .::.|               |
Human     9 LGPLLLVSLWGLLAPASLL--RR-------LGE--HIQQFQES-SAQGLGLSLGPGAAALPKVGW 61

  Fly    59 FEQRLDHFKSSDKRTWQQRYFVNADFYRNDSSAPVFLMIGGEGEASAKWMREGAWVHYAEHFGAL 123
            .||.||.|..||:|::.|||:|| |.:......|:||.:||||......:..|.....|..:|||
Human    62 LEQLLDPFNVSDRRSFLQRYWVN-DQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAPAWGAL 125

  Fly   124 CLQLEHRFYGKSHPTADLSTENLHYLSSEQALEDLASFVTAMKVKFNLGDGQKWIAFGGSYPGSL 188
            .:.|||||||.|.|...|....|.:|||..||.|:.|...|:...||:.....||.|||||.|||
Human   126 VISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWICFGGSYAGSL 190

  Fly   189 AAWAREKYPELIYGSISSSGPLLAEVDFKEYFEVVKASLAAY----KPECVDAVTRSFAQVEILL 249
            |||||.|:|.||:.|::||.|:.|.:||.||.:||..||.:.    ..||..||:.:||:||..|
Human   191 AAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLECRAAVSVAFAEVERRL 255

  Fly   250 KH-MIGQRSLDEKFKTCTPIKDSIENDLDMANFFENLAGNFAGVVQYNKDNSPHATITIDDICDV 313
            :. ...|.:|..:...|.|: ...||..::....:.|.|   |||||  |....|.:::..:|.:
Human   256 RSGGAAQAALRTELSACGPL-GRAENQAELLGALQALVG---GVVQY--DGQTGAPLSVRQLCGL 314

  Fly   314 ML----NTTAGPPVTRLGLVNDMLLKESNTTCLDYKYDKMVADMKNVSWDSETAKGMRQWTYQTC 374
            :|    |.:...|...|.....::|......||.:...:.||.:::.. ...:..|.|||.||||
Human   315 LLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLRSTE-PQLSGVGDRQWLYQTC 378

  Fly   375 HEFGFYQTSDNPADTFGDRFGVDFFIRQCMDVFSKNMNAKFLKLVVSATNDNYGALKPKTTNVLY 439
            .|||||.|.:||...|.....:...:..|..||  .::|..:...|:.||..||...|....||:
Human   379 TEFGFYVTCENPRCPFSQLPALPSQLDLCEQVF--GLSALSVAQAVAQTNSYYGGQTPGANKVLF 441

  Fly   440 VHGSIDPWHALGLVKSTNAALPTIYIEGTAHCANMYEPVKTDPPQLVAARNKILKFL 496
            |:|..||||.|.:.::..::..|:.|...:||.:|.....:|.|.|...|..|.:.|
Human   442 VNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPERPSDSPSLRLGRQNIFQQL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9953	NP_648067.2	Peptidase_S28	61..492	CDD:310284	157/439 (36%)
PRSS16	NP_005856.1	Peptidase_S28	64..494	CDD:310284	157/439 (36%)