DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10075 and C35D10.5

DIOPT Version :9

Sequence 1:	NP_648064.1	Gene:	CG10075 / 38758	FlyBaseID:	FBgn0035722	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_498013.2	Gene:	C35D10.5 / 183238	WormBaseID:	WBGene00016442	Length:	244	Species:	Caenorhabditis elegans

Alignment Length:	250	Identity:	68/250 - (27%)
Similarity:	114/250 - (45%)	Gaps:	55/250 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RLCSSTGVVDNTNKTKPGTAEAAEGGILKRVLNKV------------------GFTPNTKARLKV 86
            ||.:|:.|:.|.||.   |.|.....:|:..:::|                  |...:.|:.|..
Worm    11 RLATSSRVLSNANKK---TVEDMTQEMLQMPVSRVPPTIQRFATSLKMKFKSDGLDQSVKSILDR 72

  Fly    87 TSHLLYESVADKINYVTFFRDFNLPNTFNSWFLVTELHVWLLLMRSMAEGSETGEDGRF---LRN 148
            .|..||.:.||..::......|.|.:..:||:.:|.:|.|::|||..:|     .||:.   |:.
Worm    73 ASAQLYYNCADNYDFAKLCEAFGLGDYMSSWYKLTLMHTWMVLMRLHSE-----FDGKAYMRLQR 132

  Fly   149 CIVEAMWGDVNTR----AKKLGAHNPSRTRQ---------QIETLSEQFQAALIAYDEGIMSDDR 200
            .::..||.|::.|    :|:|   |...|.|         .::|..|        ||||.:.|||
Worm   133 GLLSTMWLDIDNRLGIVSKEL---NQIMTGQNDMKHMHGLHLQTFFE--------YDEGFLHDDR 186

  Fly   201 VLACALWRRFFEMNCD-DYAQIERLVKYVRQQASMLDSLPRDQFIVKPKVAWLEL 254
            |||.|:||..: ||.: |...:.::|.|:|...:.|::...:|.:|:....|.:|
Worm   187 VLAGAIWRCLY-MNREVDPIHLLKVVTYMRSTVAWLETQDTNQILVEGISEWKQL 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10075	NP_648064.1	Ubiq_cyt_C_chap	106..245	CDD:281912	46/155 (30%)
C35D10.5	NP_498013.2	Ubiq_cyt_C_chap	92..234	CDD:281912	47/158 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161697
Domainoid	1	1.000	62	1.000	Domainoid score	I6863
eggNOG	1	0.900	-	-		E1_KOG2873
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14709
Inparanoid	1	1.050	77	1.000	Inparanoid score	I3831
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46436
OrthoDB	1	1.010	-	-		D1428265at2759
OrthoFinder	1	1.000	-	-		FOG0004756
OrthoInspector	1	1.000	-	-		oto20399
orthoMCL	1	0.900	-	-		OOG6_103736
Panther	1	1.100	-	-	LDO	PTHR12184
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R171
SonicParanoid	1	1.000	-	-		X3909
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800