DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8549 and sbds

DIOPT Version :9

Sequence 1:	NP_001261482.1	Gene:	CG8549 / 38749	FlyBaseID:	FBgn0035714	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_957415.1	Gene:	sbds / 394096	ZFINID:	ZDB-GENE-040426-1116	Length:	231	Species:	Danio rerio

Alignment Length:	230	Identity:	139/230 - (60%)
Similarity:	175/230 - (76%)	Gaps:	2/230 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LKKGGKRFEIACYKNKVLSWRSNSEKDIDEVLQTHTVFTNVSKGQAAKKDELQKAFNKTDETEIC 85
            :||||||||||||||||:||||.:|||:||||||:|||.||||||.|||::|..||...|.||||
Zfish     1 MKKGGKRFEIACYKNKVMSWRSGAEKDLDEVLQTNTVFVNVSKGQVAKKEDLSNAFGTDDLTEIC 65

  Fly    86 KEILSKGELQVSEKERQSCLDTQLNSIVNSVAALCVNPETRRPYPASIIEKSLKDAHFSVKMNRN 150
            |:||||||||||:|||||.|:.....|...||..||||||:|||..::||:::||.|||||.|::
Zfish    66 KQILSKGELQVSDKERQSQLEQMFRDIATIVAEKCVNPETKRPYTVNLIERAMKDIHFSVKANKS 130

  Fly   151 TKQNTLEAIKILKDHMPIERSRMKLRVSFAGKEGGGKLKESVVKLANAVEHEEWDEATLHLTLLI 215
            |||..||.||.||:.:.|:|:.|:||.....|: |.:|||.:..|..|||:|::|: .|.:..||
Zfish   131 TKQQALEVIKQLKESIQIQRAHMRLRFVLPAKD-GKRLKEKLKPLIKAVENEDFDD-QLEMVCLI 193

  Fly   216 DPGQYRVIDELVRNETKGKGLLELLELKEVVESEE 250
            |||.:|.||||:|.||||||.||:|.||:|.|.:|
Zfish   194 DPGCFRDIDELIRCETKGKGTLEVLSLKDVEEGDE 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8549	NP_001261482.1	PTZ00448	4..>226	CDD:185627	122/204 (60%)
sbds	NP_957415.1	Sdo1	1..222	CDD:224417	135/222 (61%)
		SBDS	1..79	CDD:279511	60/77 (78%)
		SBDS_C	88..205	CDD:286465	57/118 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596562
Domainoid	1	1.000	145	1.000	Domainoid score	I4531
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6438
Inparanoid	1	1.050	300	1.000	Inparanoid score	I2669
OMA	1	1.010	-	-		QHG54247
OrthoDB	1	1.010	-	-		D1217666at2759
OrthoFinder	1	1.000	-	-		FOG0004811
OrthoInspector	1	1.000	-	-		oto41444
orthoMCL	1	0.900	-	-		OOG6_101125
Panther	1	1.100	-	-	LDO	PTHR10927
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1300
SonicParanoid	1	1.000	-	-		X3393
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.940