Protein Alignment eIF4E4 and tif45

DIOPT Version :10

• Sequence 1: NP_648052.1
• Gene: eIF4E4 / 38743
• FlyBaseID: FBgn0035709
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_594228.1
• Gene: tif45 / 2541706
• PomBaseID: SPAC16E8.15
• Length: 218
• Species: Schizosaccharomyces pombe
• Alignment Length: 220
• Identity: 81/220 - (36%)
• Similarity: 127/220 - (57%)
• Gaps: 16/220 - (7%)

  Fly     6 QTEFKMMDNGTETLADSPSSSSEDLKTLSDMDIRKPVTEIVDLRLKHPLENTWTLWYL-ENDRSK 69
            |||....::.||.....|...:  |:|:.|        :.::..|||||...||||:| ......
pombe     2 QTEQPPKESQTENTVSEPQEKA--LRTVFD--------DKINFNLKHPLARPWTLWFLMPPTPGL 56

  Fly    70 NWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGRWVI-NMG 133
            .|.::|..|.:|:.||:||.::|:|...|.:.:.||||.|::|::|.|||..||.||:|.. |.|
pombe    57 EWNELQKNIITFNSVEEFWGIHNNINPASSLPIKSDYSFFREGVRPEWEDVHNKTGGKWAFQNKG 121

  Fly   134 RGSKAELDKLWLDVLLILIGEAFENT-EEVCGAVINLRGKSNKISIWTANGHNELAVMEIGLKLR 197
            ||..| ||::||..:|..|||..:.| :||.|.|||:|....::::||.:.:|...:||||.:.:
pombe   122 RGGNA-LDEMWLTTVLAAIGETLDPTGQEVMGVVINMRKGFYRLAVWTKSCNNREVLMEIGTRFK 185

  Fly   198 DLLVLPPHQ-LQYQLHKDTMCKQGS 221
            .:|.||..: :::..|:|: .|.||
pombe   186 QVLNLPRSETIEFSAHEDS-SKSGS 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E4	NP_648052.1	IF4E	53..209	CDD:460281	64/159 (40%)
tif45	NP_594228.1	CDC33	1..218	CDD:227386	81/220 (37%)