DRSC/TRiP Functional Genomics Resources

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Protein Alignment axed and BTBD6

DIOPT Version :10

Sequence 1:NP_001356975.1 Gene:axed / 38741 FlyBaseID:FBgn0035708 Length:582 Species:Drosophila melanogaster
Sequence 2:NP_001374496.1 Gene:BTBD6 / 90135 HGNCID:19897 Length:538 Species:Homo sapiens


Alignment Length:345 Identity:80/345 - (23%)
Similarity:123/345 - (35%) Gaps:93/345 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   121 SAPAPSAPPAHMMPPAYARGQTNIYTGVPIIVNPYIDFIVVNGDDRYMIRCERKSVLERSV---- 181
            |||||:.||....||....                      |..:....||.|.::.||:.    
Human    89 SAPAPAPPPPAPAPPTLGN----------------------NHQESPGWRCCRPTLRERNALMFN 131

  Fly   182 -ELAKLIH---AGPNSGRKSDNHFQILNVDKNDFELIVRYMEKHFIPYRDHKHLLKILELSDRFN 242
             ||...:|   ..|.:.|....|..:|.|..:.|         :.:.|.|      :.|:....:
Human   132 NELMADVHFVVGPPGATRTVPAHKYVLAVGSSVF---------YAMFYGD------LAEVKSEIH 181

  Fly   243 VPDLIIYCIRELDLRISSATALDIFKALWFYQGIALTNQHQTVITTQETGQQLARKKATKAKAAA 307
            :||            :..|..|.:.|.::..:   :..:..||:.|              ..||.
Human   182 IPD------------VEPAAFLILLKYMYSDE---IDLEADTVLAT--------------LYAAK 217

  Fly   308 KQL--AAAKASQS-TENGAEGDGA-----QQNLIPNPNPFTTEDYGVALLHNTLQLIDMHAELQL 364
            |.:  |.|||..: .|...|...|     |..|...|.          |.....::||..||:.|
Human   218 KYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPE----------LTQRCWEVIDAQAEMAL 272

  Fly   365 SMPEISDLRFEELETLVKRDTLQLRSEVTLFECLATWSLAECARKHIDATPENRRTVLGPLCLTP 429
            ......::..:.||.:|.|:.|..: |..:||.:..|:.|||.|:.:..||.|:|.|||......
Human   273 RSEGFCEIDRQTLEIIVTREALNTK-EAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLV 336

  Fly   430 RYLRMTASEFRRCCERLELL 449
            |...||..||.....:.::|
Human   337 RIPTMTLEEFANGAAQSDIL 356

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
axedNP_001356975.1 BACK <354..423 CDD:475122 23/68 (34%)
BTBD6NP_001374496.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 29..53
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 76..115 10/47 (21%)
BTB_POZ_BTBD6 128..236 CDD:349658 28/151 (19%)
BACK_BTBD6 236..330 CDD:350600 29/104 (28%)
PHR 392..537 CDD:462339
Blue background indicates that the domain is not in the aligned region.

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