Protein Alignment axed and btbd3a

DIOPT Version :10

• Sequence 1: NP_001356975.1
• Gene: axed / 38741
• FlyBaseID: FBgn0035708
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001139053.1
• Gene: btbd3a / 563691
• ZFINID: ZDB-GENE-090312-7
• Length: 461
• Species: Danio rerio
• Alignment Length: 474
• Identity: 105/474 - (22%)
• Similarity: 163/474 - (34%)
• Gaps: 138/474 - (29%)

  Fly   172 ERKSVLERSVELAKLIH--AGPNSG-RKSDNHFQILNVDKNDFELIVRYMEKHFIPYRDHKHLLK 233
            ||.||:..: ||...||  .||..| ::...|..:|.|..:.|         |.:.|.:
Zfish    47 ERNSVMFNN-ELMADIHFVVGPPGGTQRVPGHKYVLAVGSSVF---------HAMFYGE------ 95

  Fly   234 ILELSDRFNVPDL----------IIYCIRELDLRISSATALDIFKALWFYQGIALTNQHQTVITT 288
            :.|..|...:||:          .||| .|:||..                        .||:.|
Zfish    96 LAEDKDEIRIPDVEPPSFLAMLKYIYC-DEIDLCA------------------------DTVLAT 135

  Fly   289 QETGQQLARKKATKAKAAAKQLAAAKASQSTENGAEGDGAQQN---LIPNPNPFTTEDYGVALLH 350
                           ..|||:......:::..|..|...:.:|   |:.....|...|    |..
Zfish   136 ---------------LYAAKKYIVPHLARACVNFLETSLSARNACVLLSQSCLFEEPD----LTQ 181

  Fly   351 NTLQLIDMHAELQLSMPEISDLRFEELETLVKRDTLQLRSEVTLFECLATWSLAECARKHIDATP 415
            ...::||..|||.|......|:..:.||::::|:||..: |:.:||...:|:.|||.|:.:..|.
Zfish   182 RCWEVIDAQAELALRSEGFCDIDTQTLESILRRETLNAK-EMVVFEATLSWAEAECHRQELQPTI 245

  Fly   416 ENRRTVLGPLCLTPRYLRMTASEFRRCCER---LELLPPTEISLITDALDGKKL-------KNLT 470
            ||:|.|||......|...|...:|.....:   |.|....:|.|...|....:|       |.||
Zfish   246 ENKRLVLGKSIYLIRIPAMALDDFANGVAQSGVLTLNETNDIFLWYTAAKKPELKFVCKPRKGLT 310

  Fly   471 DQQAELLEK--FRQPRAEY-----------------ARMPVHLSDRSSPKNYPKKMRLAHEG--- 513
            .|:....:.  :|..:..|                 |...::.|...|.: |..|:.|..:|
Zfish   311 PQKCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAE-YQAKIELKRQGVTL 374

  Fly   514 -----RPTEDGCWEKVGMNCLRIFV---------CIFDXSEQSDGEE-EEEEEDGDDEEE----- 558
                 :...||     ..|...:|.         ..:..|...||.| ....::|..|.:
Zfish   375 GIAIIKYFSDG-----SSNTFSVFFEYPVQIEPDTFYTASVILDGNELSYFGQEGMTEVQCGKVT 434

  Fly   559 ---DDGSDEENGNGNRAGR 574
               ...||..||.|.:.|:
Zfish   435 FQFQCSSDSTNGTGVQGGQ 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
axed	NP_001356975.1	BACK	<354..423	CDD:475122	25/68 (37%)
btbd3a	NP_001139053.1	BTB_POZ_BTBD3	38..168	CDD:349657	36/176 (20%)
		BACK_BTBD3	159..253	CDD:350599	30/98 (31%)
		PHR	315..460	CDD:462339	25/145 (17%)