Protein Alignment axed and Btbd6

DIOPT Version :10

• Sequence 1: NP_001356975.1
• Gene: axed / 38741
• FlyBaseID: FBgn0035708
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_964008.2
• Gene: Btbd6 / 399566
• MGIID: 3026623
• Length: 539
• Species: Mus musculus
• Alignment Length: 340
• Identity: 79/340 - (23%)
• Similarity: 124/340 - (36%)
• Gaps: 87/340 - (25%)

  Fly   122 APAPSAP-PAHMMPPAYARGQTNIYTGVPIIVNPYIDFIVVNGDDRYMIRCERKSVLERSVELAK 185
            ||||..| ||   ||            :|...||...    |....:....||.:::..: ||..
Mouse    93 APAPLPPLPA---PP------------LPDNNNPESP----NWQSFHPTLRERNALMFNN-ELMA 137

  Fly   186 LIH---AGPNSGRKSDNHFQILNVDKNDFELIVRYMEKHFIPYRDHKHLLKILELSDRFNVPDLI 247
            .:|   ....:.|:...|..:|.|..:.|         :.:.|.|      :.|:....::||
Mouse   138 DVHFIVGALGAARRVPAHKYVLAVGSSVF---------YAMFYGD------LAEVKSEIHIPD-- 185

  Fly   248 IYCIRELDLRISSATALDIFKALWFYQGIALTNQHQTVITTQETGQQLARKKATKAKAAAKQL-- 310
                      :..|..|.:.|.::..:   :..:..||:.|              ..||.|.:
Mouse   186 ----------VEPAAFLVLLKYMYSDE---IDLEADTVLAT--------------LYAAKKYIVP 223

  Fly   311 AAAKASQS-TENGAEGDGA-----QQNLIPNPNPFTTEDYGVALLHNTLQLIDMHAELQLSMPEI 369
            |.|||..: .|...|...|     |..|...|.          |.....::||..||:.|.....
Mouse   224 ALAKACVNFLETSLEAKNACVLLSQSRLFEEPE----------LTQRCWEVIDAQAEMALRSEGF 278

  Fly   370 SDLRFEELETLVKRDTLQLRSEVTLFECLATWSLAECARKHIDATPENRRTVLGPLCLTPRYLRM 434
            .::..:.||.:|.|:.|..: |..:||.:..|:.|||.|:.:..||.|:|.|||......|...|
Mouse   279 CEIDRQTLEIIVTREALNTK-EAVVFEAVLNWAEAECKRQGLPVTPHNKRHVLGRALYLVRIPTM 342

  Fly   435 TASEFRRCCERLELL 449
            |..||.....:.::|
Mouse   343 TLEEFANGAAQSDIL 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
axed	NP_001356975.1	BACK	<354..423	CDD:475122	23/68 (34%)
Btbd6	NP_964008.2	BTB_POZ_BTBD6	129..237	CDD:349658	27/152 (18%)
		BACK_BTBD6	237..331	CDD:350600	29/104 (28%)
		PHR	393..538	CDD:462339