Protein Alignment axed and BTBD17

DIOPT Version :9

• Sequence 1: NP_001356975.1
• Gene: axed / 38741
• FlyBaseID: FBgn0035708
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_011523093.1
• Gene: BTBD17 / 388419
• HGNCID: 33758
• Length: 479
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 72/392 - (18%)
• Similarity: 117/392 - (29%)
• Gaps: 146/392 - (37%)

  Fly   171 CERKSVLERSVELAKL----IHAGPNSGRKSDNHFQILNVDKNDFELIVRYMEKHFIPYRDHKHL 231
            |......:....||.|    ...|..:...|.||.|.:                          |
Human    13 CREPETFQGEARLALLGAQRADVGGEAAGTSINHSQAV--------------------------L 51

  Fly   232 LKILELSDRFNVPDLIIYCIRELDLRISSA--TALDIFKALWFYQGI-------ALTNQHQ---- 283
            .::.||..:.|..|::        ||:.:|  ..:.:|.|.....|:       .|:||.:
Human    52 QRLQELLRQGNASDVV--------LRVQAAGTDEVRVFHAHRLLLGLHSELFLELLSNQSEAVLQ 108

  Fly   284 ---------------------TVITTQETGQQLARKKATKAKAAAKQLAAAKASQSTENGAEGDG 327
                                 ||:.||...   ..:.|||...::.|...|...::...|..|..
Human   109 EPQDCAAVFDKFIRYLYCGELTVLLTQAIP---LHRLATKYGVSSLQRGVADYMRAHLAGGAGPA 170

  Fly   328 AQQNLIPNPNPFTTEDYGV-----ALLHNTLQLIDMHAELQLSMPEISDLRFEELETLVKRDTLQ 387
            .           ....|.|     ||..:.||.:..:.....:..|...:..|.|..|::|..|.
Human   171 V-----------GWYHYAVGTGDEALRESCLQFLAWNLSAVAASTEWGAVSPELLWQLLQRSDLV 224

  Fly   388 LRSEVTLFECLATWSLAECARKHIDATPENRRTVLG----PLCLTPRYLRMTASEFRRCCERLEL 448
            |:.|:.||..|..|                    ||    |..:..|.||..         |..:
Human   225 LQDELELFHALEAW--------------------LGRARPPPAVAERALRAI---------RYPM 260

  Fly   449 LPPTEISLITD-----ALDGKKLKNLTDQQAELLEKFRQPRAEYARMPVHLS-------DRSSPK 501
            :||.::..:..     |..|..:.:|      ||:.::    .:|..|:|.:       ....|:
Human   261 IPPAQLFQLQARSAALARHGPAVADL------LLQAYQ----FHAASPLHYAKFFDVNGSAFLPR 315

  Fly   502 NY 503
            ||
Human   316 NY 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
axed	NP_001356975.1	BTB	<192..258	CDD:197585	10/65 (15%)
		BACK	<354..423	CDD:355779	13/68 (19%)
BTBD17	XP_011523093.1	BTB	54..159	CDD:279045	22/115 (19%)
		BTB	65..163	CDD:197585	19/108 (18%)
		BACK	170..268	CDD:197943	27/137 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900