Protein Alignment axed and Btbd3

DIOPT Version :10

• Sequence 1: NP_001356975.1
• Gene: axed / 38741
• FlyBaseID: FBgn0035708
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_663509.2
• Gene: Btbd3 / 228662
• MGIID: 2385155
• Length: 530
• Species: Mus musculus
• Alignment Length: 284
• Identity: 68/284 - (23%)
• Similarity: 109/284 - (38%)
• Gaps: 77/284 - (27%)

  Fly   172 ERKSVLERSVELAKLIH--AGPNSG-RKSDNHFQILNVDKNDFELIVRYMEKHFIPYRDHKHLLK 233
            ||.:|:..: :|...:|  .||..| ::...|..:|.|..:.|         |.:.|.:
Mouse   116 ERNAVMFNN-DLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVF---------HAMFYGE------ 164

  Fly   234 ILELSDRFNVPDL----------IIYCIRELDLRISSATALDIFKALWFYQGIALTNQHQTVITT 288
            :.|..|...:||:          .||| .|:||      |.|                  ||:.|
Mouse   165 LAEDKDEIRIPDVEPAAFLAMLKYIYC-DEIDL------AAD------------------TVLAT 204

  Fly   289 QETGQQLARKKATKAKAAAKQLAAAKASQSTENGAEGDGAQQN---LIPNPNPFTTEDYGVALLH 350
                           ..|||:......:::..|..|...:.:|   |:.....|...|    |..
Mouse   205 ---------------LYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPD----LTQ 250

  Fly   351 NTLQLIDMHAELQLSMPEISDLRFEELETLVKRDTLQLRSEVTLFECLATWSLAECARKHIDATP 415
            ...::||..|||.|......|:.|:.||::::|:||..: |:.:||....|:..||.|:.:..:.
Mouse   251 RCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAK-EIVVFEAALNWAEVECQRQDLALSI 314

  Fly   416 ENRRTVLGPLCLTPRYLRMTASEF 439
            ||:|.|||......|...|...:|
Mouse   315 ENKRKVLGKALYLIRIPTMALDDF 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
axed	NP_001356975.1	BACK	<354..423	CDD:475122	24/68 (35%)
Btbd3	NP_663509.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	23..48
		BTB_POZ_BTBD3	107..237	CDD:349657	35/176 (20%)
		BACK_BTBD3	228..322	CDD:350599	29/98 (30%)
		PHR	384..529	CDD:462339