Protein Alignment axed and BTBD19

DIOPT Version :10

• Sequence 1: NP_001356975.1
• Gene: axed / 38741
• FlyBaseID: FBgn0035708
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_011539105.1
• Gene: BTBD19 / 149478
• HGNCID: 27145
• Length: 470
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 49/302 - (16%)
• Similarity: 86/302 - (28%)
• Gaps: 123/302 - (40%)

  Fly   104 VLPFGLGPDG---------HHVDAIQSAPAPSAPP-AHMMPPAYARGQTNIYTGVPIIVNPYIDF 158
            :|..|||..|         |:.........||.|| .|......|.....::.|
Human   103 LLTRGLGGRGGGCQRQEFAHYTVGTGQGKLPSTPPTTHSTGAGSADSGCGVWAG----------- 156

  Fly   159 IVVNGDDRYMIRCE----RKSVLERSVELAKLIHAGPNSGRKSDNHFQILNVDKNDFELIVRYME 219
                |.:|....|:    ...:|..|:......|:|                           :|
Human   157 ----GTERGGFLCQVPVSFPLLLTGSLPALPHTHSG---------------------------LE 190

  Fly   220 KHFIPYRDH---------KHLLKI---------LELSDRFNVPDLIIYCIRELD----------- 255
            ::..|:|:.         :.::|:         |:::..|.:..|...|:..::
Human   191 RNVCPHREKYVYLSQLCLQFVVKVLDVDLVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRG 255

  Fly   256 -LRISSATALDIFKA---------------LWFYQGIALTNQHQTVITTQETGQQLARKKATKAK 304
             |.:|:|..|.:.::               .|...|.|:                |.|..|..|.
Human   256 FLELSAAALLPLLRSDKLCVDEAELVRAARSWARVGAAV----------------LERPVAEVAA 304

  Fly   305 AAAKQLAAAKASQSTENGAEGDGAQQNLIP------NPNPFT 340
            ...|:|..|..:.:..:..|....|:.|||      .|.|.:
Human   305 PVVKELRLALLAPAELSALEEQNRQEPLIPVGTRGTGPAPLS 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
axed	NP_001356975.1	BACK	<354..423	CDD:475122
BTBD19	XP_011539105.1	BTB_POZ_BTBD19	15..>101	CDD:349603
		BACK_BTBD19	221..288	CDD:350569	8/66 (12%)