Protein Alignment Mdr65 and CG1824

DIOPT Version :10

• Sequence 1: NP_476831.1
• Gene: Mdr65 / 38726
• FlyBaseID: FBgn0004513
• Length: 1302
• Species: Drosophila melanogaster
• Sequence 2: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Alignment Length: 604
• Identity: 209/604 - (34%)
• Similarity: 326/604 - (53%)
• Gaps: 54/604 - (8%)

  Fly   109 NNEALYDDSISYGILLTIASVVMFISGIFSVDVF--NMVALRQVTRMRIKLFSSVIRQDIGWHDL 171
            ||..:.|.|.....||   |:.|..||...:.::  :.|..:...:||..||:.::.|||.:.|
  Fly   174 NNSFVKDVSKPASNLL---SLYMLQSGFTFMYIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFD- 234

  Fly   172 ASKQNFTQSMVD----DVEKIRDG----ISEKVGHFVYLVVGFIITVAISFSYGWKLTLAVSSYI 228
               :|.|..:|:    ||:..:..    :|:.:.....|:.|.|....||   .....:|::| :
  Fly   235 ---ENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMIS---PHMAAIALAS-V 292

  Fly   229 PLVILLNYYVAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKA 293
            |.|::...|:.|....|:...|.....|..:.||.||:||||.|...|..|:|.:|.....|.:.
  Fly   293 PCVVMFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAARL 357

  Fly   294 SQWKG----AFSGLSDAVLKSMLYLSCAGAFWYGVNLIIDDRNVENKEYTPAILMIAFFGIIVGA 354
            :|..|    .|.||::..|.: |.||         .|.:....:..:..:|..|| ||.....|.
  Fly   358 AQKLGYGIAIFQGLTNFFLNT-LVLS---------TLFMGGHLMSTESLSPGALM-AFLVASQGV 411

  Fly   355 D-NIARTAPFLESFATARGCATNLFKVIDLTSKIDPLSTDGKLL-NYGLRGDVEFQDVFFRYPSR 417
            . ::|:.:..|.:........:.:|:.:.|..:::.|.  |.:: ...|.|::.|::|.|.||.:
  Fly   412 QRSLAQGSILLGTMIRGMSAGSRVFEFLSLQPQVELLR--GYIIPQERLHGEIRFENVSFAYPMQ 474

  Fly   418 PEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQWLRSN 482
            |:.:|.:..::.:|.||||||||:||.||||...|::|||:|..|::.||...:...:..|||||
  Fly   475 PDHLVLKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSN 539

  Fly   483 I-AVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAATQAGAHEFITNLPESYRSMIGERGSQLSG 546
            : ..:.|:||||..:|.:||.||||.|.::::.|||..:.:|:|:|.||:.|.:.:||||:||||
  Fly   540 VLGFIEQQPVLFGTSILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSG 604

  Fly   547 GQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIVVSHRLSAIRGADKI 611
            ||:|||||||||::||:||:|||||||||..||.:||:|||...:.|||:|::||||.||.||.|
  Fly   605 GQRQRIAIARALLKNPRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLI 669

  Fly   612 VFIHDGKVLEEGSHDDLMALEGAYYNMVRAGDINMPDEVEKEDSIED-----------TKQKSLA 665
            |.:..|:|:|.|.||:||...|.|:.:||..:  ..|..|:..::||           |:..:.|
  Fly   670 VVLDQGRVVETGKHDELMGKRGLYFELVRQQE--RRDIQEQVQAVEDVVAVKEQQATATETSTAA 732

  Fly   666 LFEKSFETSPLNFEKGQKN 684
            ....:.|||......|..:
  Fly   733 TIATAAETSAATVTVGSSS 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdr65	NP_476831.1	MdlB	118..641	CDD:440747	194/539 (36%)
		MdlB	711..1299	CDD:440747
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	199/553 (36%)