Protein Alignment Prdm13 and ZNF366

DIOPT Version :9

• Sequence 1: NP_648032.1
• Gene: Prdm13 / 38713
• FlyBaseID: FBgn0035687
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_689838.1
• Gene: ZNF366 / 167465
• HGNCID: 18316
• Length: 744
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 68/317 - (21%)
• Similarity: 105/317 - (33%)
• Gaps: 79/317 - (24%)

  Fly   173 LNIQGNSRYMCHLCHLTF-ETPH---------PLKIHLALGCGRSAMDILWMRLHYALKAAARS- 226
            |..||...:.|.:||..| :|.|         .:|.|....|||.......::.|.|..|:.|.
Human   301 LTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSEVKPHNCRVCGRGFAYPSELKAHEAKHASGREN 365

  Fly   227 -----------------HTETQHSPIPATSSTSSASPTHSPPPQMP---PRFSAFRPIAALTQSL 271
                             |..|...||  ..:.|....|...|.|:.   .:....||.......:
Human   366 ICVECGLDFPTLAQLKRHLTTHRGPI--QYNCSECDKTFQYPSQLQNHMMKHKDIRPYICSECGM 428

  Fly   272 PMVPVTTAATPLSYLPSMSMATAPLSTNPMNAAAQIEAIVSNM------GASKQGHLCIYCGKVY 330
            ..|..       .:|...|:....:..:......:...:::||      ..:.:.:.|..|.|.:
Human   429 EFVQP-------HHLKQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCYKSF 486

  Fly   331 SRKYGLKIHIRTHTGFKPLKCKFCLRPFGDPSNLNKHVRLHLQTHPSSSAGVADGGASGADMDGD 395
            .:|..||.|:..|:..||.|||.|.:.|....||..|:.||..:.|
Human   487 VQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHMHLHSDSKP------------------- 532

  Fly   396 VDIEGETDADYQCHVCHKSFPRRRDLQRHMETRHG----GHHSHSHSESRSSSTSTS 448
                      ::|..|...|..:.:|.|||:.:||    |.||......|.:...|:
Human   533 ----------FKCLYCPSKFTLKGNLTRHMKVKHGVMERGLHSQGLGRGRIALAQTA 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prdm13	NP_648032.1	COG5048	280..>380	CDD:227381	25/105 (24%)
		C2H2 Zn finger	323..343	CDD:275368	7/19 (37%)
		zf-H2C2_2	336..358	CDD:290200	10/21 (48%)
		C2H2 Zn finger	351..371	CDD:275368	7/19 (37%)
		zf-C2H2	406..427	CDD:278523	7/20 (35%)
		C2H2 Zn finger	408..427	CDD:275368	7/18 (39%)
ZNF366	NP_689838.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..228
		COG5048	253..>549	CDD:227381	57/285 (20%)
		C2H2 Zn finger	255..275	CDD:275368
		C2H2 Zn finger	283..303	CDD:275368	1/1 (100%)
		C2H2 Zn finger	311..331	CDD:275368	6/19 (32%)
		C2H2 Zn finger	339..359	CDD:275368	5/19 (26%)
		C2H2 Zn finger	367..387	CDD:275368	1/19 (5%)
		C2H2 Zn finger	395..415	CDD:275368	4/19 (21%)
		C2H2 Zn finger	423..443	CDD:275368	3/26 (12%)
		C2H2 Zn finger	451..471	CDD:275368	2/19 (11%)
		Interaction with NRIP1. /evidence=ECO:0000269|PubMed:17085477	455..744		37/154 (24%)
		C2H2 Zn finger	479..499	CDD:275368	7/19 (37%)
		C2H2 Zn finger	507..527	CDD:275368	7/19 (37%)
		C2H2 Zn finger	535..554	CDD:275368	7/18 (39%)
		PXDLS. /evidence=ECO:0000269|PubMed:16393996, ECO:0000269|PubMed:17085477	590..594
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	603..627
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	664..692

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000