Protein Alignment loj and TMED1

DIOPT Version :8

• Sequence 1: NP_648027.3
• Gene: loj / 38698
• FlyBaseID: FBgn0061492
• Length: 237
• Species: Drosophila melanogaster
• Sequence 2: NP_006849.1
• Gene: TMED1 / 11018
• HGNCID: 17291
• Length: 227
• Species: Homo sapiens
• Alignment Length: 188
• Identity: 43/189 (23%)
• Similarity: 88/189 (47%)
• Gaps: 12/189 (6%)

  Fly    52 IDAGKEDCYHQYVKAGATFYVSFSVVRGGDGM-AGFAVRNPAGEVVKPYQWQATADYTDQVSPGG 115
            :.||::.|::|...|.|:....:.|: ||.|: ..|.:.:|.|.::.....:|...:|.:.:..|
Human    38 LPAGRKQCFYQSAPANASLETEYQVI-GGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAG 101

  Fly   116 YYSVCIDNQFSRFAGKLVNIYITVV--------KYDAWDKYAKEIEQLQLNMQNFTATVGTVERN 172
            .|.:|.||.||..:.|||  :..::        :.:.|.:..:..|.|.:.|::...::.|:...
Human   102 DYKLCFDNSFSTISEKLV--FFELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTR 164

  Fly   173 INDMMGYQAHSRHRESRDYALLLDNNAYIQTFSISQIVVILITCSVQVFFVRKLFEVK 230
            :...:......|..|:||..|...|...:..:|...:.|:|:...:||..:::.|:.|
Human   165 LERSIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDK 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
loj	NP_648027.3	EMP24_GP25L	47..228	CDD:279450	42/185 (23%)
TMED1	NP_006849.1	EMP24_GP25L	33..220	CDD:307313	42/185 (23%)
		COPI vesicle coat-binding. {ECO:0000255}	218..227		2/6 (33%)
		COPII vesicle coat-binding. {ECO:0000255}	218..219		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG1693
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900