Protein Alignment CG10472 and KLK8

DIOPT Version :10

• Sequence 1: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 80/267 - (29%)
• Similarity: 115/267 - (43%)
• Gaps: 27/267 - (10%)

  Fly    22 WNSVKNLNIETPMPKVHGET-LPSGRITGGQIAEPNQFPYQVGLLLYITGGAAWCGGTIISDRWI 85
            |.|       .|:|...|.: ....::.||...:|:..|:|..|   ..|....|||.::...|:
Human    59 WRS-------NPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAAL---FQGQQLLCGGVLVGGNWV 113

  Fly    86 ITAAHCTDSLTTGVDVYLGAHDRTNAKEEGQQIIFVETKNVIVHEDWIAETI---TNDISLIKLP 147
            :|||||.....|   |.||.|...|.....|:|..|::   |.|..:.:..:   .:|:.|::|.
Human   114 LTAAHCKKPKYT---VRLGDHSLQNKDGPEQEIPVVQS---IPHPCYNSSDVEDHNHDLMLLQLR 172

  Fly   148 VPIEFNKYIQPAKLPVKSDSYSTYGGENAIASGWGKISDSATGATDILQYATVPIMNNSGCSPWY 212
            ........::|..|.    .:.|..|:....||||.::.......|.|..|.|.|.....|...|
Human   173 DQASLGSKVKPISLA----DHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAY 233

  Fly   213 FGLVAASNICIKTTGGISTCNGDSGGPLVLDDGSNTLIGATSFGIALGCEVGWPGVFTRITYYLD 277
            .|.:....:|..::.|..||.||||||||.|   ..|.|.||:|.........|||:|.|..|||
Human   234 PGQITDGMVCAGSSKGADTCQGDSGGPLVCD---GALQGITSWGSDPCGRSDKPGVYTNICRYLD 295

  Fly   278 WIEEKSG 284
            ||::..|
Human   296 WIKKIIG 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	72/235 (31%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	72/235 (31%)