DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yip7 and TMPRSS11F

DIOPT Version :9

Sequence 1:	NP_523944.1	Gene:	yip7 / 38680	FlyBaseID:	FBgn0040060	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_997290.2	Gene:	TMPRSS11F / 389208	HGNCID:	29994	Length:	438	Species:	Homo sapiens

Alignment Length:	253	Identity:	87/253 - (34%)
Similarity:	125/253 - (49%)	Gaps:	32/253 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SITGRITNGKD-AVAGQFPYQVGLSFSSSAGSWWCGGSIIGNEWVLTAAHC-------TDGAASV 91
            |.|.||..|:: |:.|::|:|..|....|...  ||.|:|.|.|:||||||       |...|:
Human   201 SSTQRIVQGRETAMEGEWPWQASLQLIGSGHQ--CGASLISNTWLLTAAHCFWKNKDPTQWIAT- 262

  Fly    92 TIYYGATVRTSPEFTQVVSSSKFRQHESYLALTIRNDISLIQTSS-VSFSATVNKISLPAVSNSY 155
               :|||: |.|...:.|  .|...||:|...|..|||:|:|.|: |.||..|.::.||   :|.
Human   263 ---FGATI-TPPAVKRNV--RKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLP---DSS 318

  Fly   156 STYEGKTAV-ASGWGLTSDQATAVSRDLQYVDLTIISNSKC--QETFGSLIVTSRVLCVD-TTNK 216
            .....||:| .:|:|...|.. .:...|:...:..||...|  ::.:..|| |..:||.. ...|
Human   319 IKLPPKTSVFVTGFGSIVDDG-PIQNTLRQARVETISTDVCNRKDVYDGLI-TPGMLCAGFMEGK 381

  Fly   217 ASTCQGDSGGPLALDG----VLIGATSFGSADGCESGAPAAFTRITYYRDWIKETSGI 270
            ...|:|||||||..|.    .::|..|:|.:..... .|..:||:|.|||||...:|:
Human   382 IDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPK-KPGVYTRVTKYRDWIASKTGM 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yip7	NP_523944.1	Tryp_SPc	39..264	CDD:214473	82/241 (34%)
yip7	NP_523944.1	Tryp_SPc	40..267	CDD:238113	83/243 (34%)
TMPRSS11F	NP_997290.2	SEA	59..154	CDD:279699
		Tryp_SPc	205..432	CDD:214473	82/241 (34%)
		Tryp_SPc	206..435	CDD:238113	83/243 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910