DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18586 and AAE17

DIOPT Version :9

Sequence 1:	NP_647993.2	Gene:	CG18586 / 38659	FlyBaseID:	FBgn0035642	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_197696.2	Gene:	AAE17 / 832369	AraportID:	AT5G23050	Length:	721	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	117/563 - (20%)
Similarity:	213/563 - (37%)	Gaps:	105/563 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 EDIVLT-----REDLHMNAMRV----------ASYMRNMGLGQTDIVGV-MGRHTTHQSAVAY-A 108
            :|||:.     .:||.:|.|.:          |..:..:||.:...:.| |..:.  :|.:.| |
plant   184 DDIVIRWRDEGSDDLPVNTMTLLELRSQVWLAAHALSALGLEEESAIAVDMPMNV--ESVIIYLA 246

  Fly   109 CFFNGTPLHALHNAYEEACIAKLFGITKPRLIFCD-----GDE----YEKVKSATKDLQVTIVTM 164
            ....|..:.::.:::....|:....|:|.:.||..     ||:    |.:|..|...|.:.:...
plant   247 IVLAGHVVVSIADSFSPREISTRLKISKAKAIFTQDVIIRGDKSIPLYRRVVDAEAPLAIVVPAR 311

  Fly   165 RNHPRGSVRIQDVLTTPVMQNFQPLRLKDGIDHTLA---------ILSSSGTSGFPKAVTISNSH 220
            .:..|..:|.:|:.....:.|.:.||   |:::..|         ||.||||:|.|||:..:|..
plant   312 GSSCRMKLREKDLSWNNFLGNARNLR---GVEYVAAEKPAGAYTNILFSSGTTGEPKAIPWTNIS 373

  Fly   221 --KIIVD---YMAINNSNIQYTSSTLDWCSGLSMAITS-------GVFSTTSIIADCDFDPGLFC 273
              |...|   ::.:...::....:.|.|..|..:...|       |:::.:.:      .| .|.
plant   374 PLKSAADAWCHLDVQRGDVVAWPTNLGWMMGPWLVYASLINGACMGLYNGSPL------GP-TFA 431

  Fly   274 RAIGKYRISMVLLSSSYLAIFANCPEFESADLSSLNYVIFG--GSSCSLEVQRKVRSRLSH-DCL 335
            :.:....:|::.:..|.:..:.|.......|.|.:.  .||  |.:.:::....:..|..: ..:
plant   432 KFVQDAEVSVLGVIPSIVRTWQNSNSTSGYDWSRIR--CFGSTGEASNIDEYLWLMGRAHYKPVI 494

  Fly   336 NFCYGLTELNS---AGSVNLNFDEKPNSV---GRAIRGIKIKVIDEQGEAQEPNV--VGE--ICF 390
            .:|.| ||:..   :||:     .:|.|:   ..|..|.|:.::||......|..  |||  :|.
plant   495 EYCGG-TEIGGSFISGSL-----LQPQSLAAFSTAAMGCKLFILDEDSNPIPPYAAGVGELALCP 553

  Fly   391 H---------NSQKWAGYYKN-PDETRQIQDSENWIHTGDLGYVDKDGYLFVIDRLKDMLKYQNI 445
            |         |...:..|::. |....||....     |||......||.....|..|.:....|
plant   554 HMFGASSTLLNGNHFKVYFQGMPTFQGQILRRH-----GDLFERTSKGYYRAHGRADDTMNLGGI 613

  Fly   446 MYYPSEIENVIAEM-PNVLEACVFGIWDPVNGDEAAASLV-------KKPGTQLEAQDVVEYVRK 502
            .....|||.|...: .:|||....|:..|..|.|.....|       ..|...|..:.....::|
plant   614 KVGSIEIERVCNSVDDSVLETAAIGVPPPSGGPEQLVIAVVFKSPEFSNPDLNLLKKSFNSEIQK 678

  Fly   503 RITAKFKQLNGGALIVDQIVRSGNRKTNRSAVKEHFLKNYNNN 545
            ::...||.  ...:.:..:.|:...|..|..:::...:...|:
plant   679 KLNPLFKV--SSVVTLPSLPRTATNKVMRRVLRQQLTQTGLNS 719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	116/557 (21%)
CG18586	NP_647993.2	AFD_class_I	55..530	CDD:302604	115/546 (21%)
AAE17	NP_197696.2	PLN03052	1..721	CDD:215553	117/563 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910