Protein Alignment CG18586 and ACSBG2

DIOPT Version :9

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001276106.1
• Gene: ACSBG2 / 81616
• HGNCID: 24174
• Length: 666
• Species: Homo sapiens
• Alignment Length: 664
• Identity: 122/664 - (18%)
• Similarity: 227/664 - (34%)
• Gaps: 230/664 - (34%)

  Fly    26 GREAPSLFSPNLSIGEIIFGDMVNN----PKLIAQISITEDIVLTREDLHMNAMRVASYMRNMGL 86
            |.|.|      ::|.| .|.:.||.    |.|.::.....:| |.....:....:.|..:..:||
Human    46 GHETP------MTIPE-FFRESVNRFGTYPALASKNGKKWEI-LNFNQYYEACRKAAKSLIKLGL 102

  Fly    87 GQTDIVGVMGRHTTHQSAVAYACFFNG---TPLHALHNAYEEACIAKLFGIT--KPRLIFCDGDE 146
            .:...||::|.::......|......|   ..::|.::|  |.|   .:.||  |..::..:.|:
Human   103 ERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATNSA--EVC---QYVITHAKVNILLVENDQ 162

  Fly   147 YEKVKSATKDLQVTIVTMRNHPRGSVRIQDVLTTPVMQNFQPLR--------------------- 190
                                      ::|.:|:.| ..:.:||:
Human   163 --------------------------QLQKILSIP-QSSLEPLKAIIQYRLPMKKNNNLYSWDDF 200

  Fly   191 -----------LKDGIDHTLA-----ILSSSGTSGFPKAVTIS------------------NSHK 221
                       |:..|:...|     ::.:|||:|.||.|.:|                  :.|:
Human   201 MELGRSIPDTQLEQVIESQKANQCAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFKLTDKHE 265

  Fly   222 IIVDYMAINNSNIQYTS------------------------STLD-------------W------ 243
            .:|.|:.:::...|...                        |||.             |
Human   266 TVVSYLPLSHIAAQMMDIWVPIKIGALTYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEM 330

  Fly   244 ---CSGLSMAITSGVFSTTSIIADCDFDPGLFCRAIG----------------KYRISMVLLSSS 289
               .|..||.:....|              ::.|.||                .||::..|:.|.
Human   331 VKKNSAKSMGLKKKAF--------------VWARNIGFKVNSKKMLGKYNTPVSYRMAKTLVFSK 381

  Fly   290 YLAIFA--NCPEFESADLSSLNYVIFGGSSCSLEVQRKVRSRLSHDC-LNFCYGLTELNSAGSVN 351
            ......  :|..|.|. .:.||             |......||.|. :...|||:|.:...:::
Human   382 VKTSLGLDHCHSFISG-TAPLN-------------QETAEFFLSLDIPIGELYGLSESSGPHTIS 432

  Fly   352 LNFDEKPNSVGRAIRGIKIKVIDEQGEAQEPNVVGEICFHNSQKWAGYYKNPDETRQIQDSENWI 416
            ...:.:..|.|:.:.|.|..:..     |..:.:||||......:.||.::..||.:..|.|.|:
Human   433 NQNNYRLLSCGKILTGCKNMLFQ-----QNKDGIGEICLWGRHIFMGYLESETETTEAIDDEGWL 492

  Fly   417 HTGDLGYVDKDGYLFVIDRLKDML---KYQNIMYYPSEIENVI-AEMPNVLEACVFG-------- 469
            |:||||.:|..|:|:|...:|::|   ..:|:.  |..:|.:: .::|.:..|.:.|
Human   493 HSGDLGQLDGLGFLYVTGHIKEILITAGGENVP--PIPVETLVKKKIPIISNAMLVGDKLKFLSM 555

  Fly   470 ------IWDPVNGDE------AAASLVKKPGTQLEAQDVVEYVRKRITAKFKQLNGGALIVDQIV 522
                  ..:.::|:.      .|.:..:..|:|  |..|.|.|:::....:|.:..|...|:|..
Human   556 LLTLKCEMNQMSGEPLDKLNFEAINFCRGLGSQ--ASTVTEIVKQQDPLVYKAIQQGINAVNQEA 618

  Fly   523 RSGNRKTNRSAVKE 536
            .:..::..:..:.|
Human   619 MNNAQRIEKWVILE 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	119/655 (18%)
		AFD_class_I	55..530	CDD:302604	111/623 (18%)
ACSBG2	NP_001276106.1	ACSBG_like	73..665	CDD:341256	112/630 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149062
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930