DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18586 and Slc27a2

DIOPT Version :9

Sequence 1:	NP_647993.2	Gene:	CG18586 / 38659	FlyBaseID:	FBgn0035642	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_113924.2	Gene:	Slc27a2 / 65192	RGDID:	71103	Length:	620	Species:	Rattus norvegicus

Alignment Length:	532	Identity:	110/532 - (20%)
Similarity:	207/532 - (38%)	Gaps:	84/532 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 DIVLTREDLHMNAMRVASYMR-NMGLGQTDIVGV-MGRHTTHQSAVAYACFF-----NGTPLHAL 119
            |..||...:...:.:||..:. ::||.|.|.|.: ||...      ||...:     .|.|:..|
  Rat    76 DETLTYAQVDRRSNQVARALHDHLGLRQGDCVALFMGNEP------AYVWLWLGLLKLGCPMACL 134

  Fly   120 HNAYEEACIAKLFGITKPRLIFCDGDEYEKVKSATKDLQ-----VTIVTMRNHPRGSVRIQD--- 176
            :.......:...|.....:::....:.:|.|:.....|:     |..|:..::..|...:.|
  Rat   135 NYNIRAKSLLHCFQCCGAKVLLASPELHEAVEEVLPTLKKEGMSVFYVSRTSNTNGVDTVLDKVD 199

  Fly   177 -VLTTPVMQNFQPLRLKDGIDHTLAILSSSGTSGFPKAVTISNSHKI-----IVDYMAINNSNIQ 235
             |...|:.:::   |.:.........:.:|||:|.|||.|| |.|::     :.....|...::.
  Rat   200 GVSADPIPESW---RSEVTFTTPAVYIYTSGTTGLPKAATI-NHHRLWYGTSLALRSGIKAHDVI 260

  Fly   236 YTSSTLDWCSGLSMAITSGVFSTTSIIADCDFDPGLF---CRAIGKYRISMVLLSSSYLAIFANC 297
            ||:..|...:.|.:.:...:....:......|....|   ||   ||..:::......|....|.
  Rat   261 YTTMPLYHSAALMIGLHGCIVVGATFALRSKFSASQFWDDCR---KYNATVIQYIGELLRYLCNT 322

  Fly   298 PEFESADLSSLNYVIFGGSSCSLEVQRKVRSRLSHDCLNFCYGLTELNSAGSVN-LNFDEKPNSV 361
            |:..:.....:...:  |:....:|.|:...|.....:...|..||    |::. :|:..|..:|
  Rat   323 PQKPNDRDHKVKIAL--GNGLRGDVWREFIKRFGDIHIYEFYASTE----GNIGFMNYPRKIGAV 381

  Fly   362 GR-------AIRGIKIKVIDEQGE-AQEPN------VVGE----IC-FHNSQKWAGYY--KNPDE 405
            ||       .:|...||...|:.| .::.|      ..||    || ......:.||.  |...|
  Rat   382 GRENYLQKKVVRHELIKYDVEKDEPVRDANGYCIKVPKGEVGLLICKITELTPFFGYAGGKTQTE 446

  Fly   406 TRQIQD----SENWIHTGDLGYVDKDGYLFVIDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEAC 466
            .::::|    .:.:.::|||..:|::.:::..||:.|..:::......:|:.:::..:..|.|..
  Rat   447 KKKLRDVFKKGDVYFNSGDLLMIDRENFIYFHDRVGDTFRWKGENVATTEVADIVGLVDFVEEVN 511

  Fly   467 VFGIWDPVNGDE---AAASLVKKPGTQLEA----QDVVEYVRKRITAKFKQLNGGALIVDQIVRS 524
            |:|:  ||.|.|   ..||:..|...:...    |.:.||:......:|.:      |.|.|..:
  Rat   512 VYGV--PVPGHEGRIGMASIKMKENYEFNGKKLFQHISEYLPSYSRPRFLR------IQDTIEIT 568

  Fly   525 GNRKTNRSAVKE 536
            |..|..:..:.|
  Rat   569 GTFKHRKVTLME 580

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	110/532 (21%)
CG18586	NP_647993.2	AFD_class_I	55..530	CDD:302604	109/524 (21%)
Slc27a2	NP_113924.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	110/532 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342944
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930