Protein Alignment CG18586 and CG4563

DIOPT Version :9

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_611913.1
• Gene: CG4563 / 37901
• FlyBaseID: FBgn0035006
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 527
• Identity: 181/527 - (34%)
• Similarity: 291/527 - (55%)
• Gaps: 9/527 - (1%)

  Fly    17 YDDKLKIWSGREAPSLFSPNLSIGEIIFGDMVNNPKLIAQISITEDIVLTREDLHMNAMRVASYM 81
            ::.:.::|||...|:::..|.|:|:|:|..:...|..:.||:..:..|||..|:...|.|:|.:.
  Fly    11 FNKETQVWSGPPRPTVYDHNTSVGQIVFNSLRCWPTNVIQITDDDGTVLTNADMLAYATRIALFF 75

  Fly    82 RNMGLGQTDIVGVMGRHTTHQSAVAYACFFNGTPLHALHNAYEEACIAKLFGITKPRLIFCDGDE 146
            ::.||.|.|.||::...:|....||.||||..||.||::.:.|.|.:..|:.:|||:::|.||.:
  Fly    76 KSEGLTQEDRVGIIANSSTFVIPVATACFFQATPFHAVNYSREPAIVQGLYSVTKPKIMFIDGPD 140

  Fly   147 YEKVKSATKDLQVTIVTMRNHPRGSVRIQDVLTT-PVMQNFQPLRLKDGIDHTLAILSSSGTSGF 210
            |:::|..||:....::|:.....|...|:|::.. |..:.:.|..|..|.|....:|.||||:|.
  Fly   141 YDRIKEITKEWSPKLITLTGKVEGVTSIEDLVKPHPAEKIYVPASLATGGDQIAVVLCSSGTAGL 205

  Fly   211 PKAVTISNSHKIIVDYMAINNSNIQYTSSTLDWCSGLSMAITSGVFSTTSIIADCDFDPGLFCRA 275
            ||||.:|:.|....:.:.| ::::.|||:|:||.:|.|:.:.:.....|.||:...|........
  Fly   206 PKAVALSHRHIASTNSLCI-STDVLYTSATIDWMTGFSITVMNLTCGFTRIISRRTFSAETALYL 269

  Fly   276 IGKYRISMVLLSSSYLAIFANCPEFESADLSSLNYVIFGGSSCSLEVQRKVRSRLSHDCLNFCYG 340
            :.||:::.:.::..........|...|..|.||......|...||.:.|:.:..|....:.|.||
  Fly   270 VSKYKVTCLAMAPWQAYELFTSPLATSEQLESLKIAFVIGGWISLALLRRAQELLPKTYVMFSYG 334

  Fly   341 LTELNSAGSVNLNFDEKPN-SVGRAIRGIKIKVIDEQGEAQEPNVVGEICFHNSQKWAGYYKNPD 404
            .||   .|.|.:|.|.... ||||...|::||:..|.|:....|..||:......||.||..||:
  Fly   335 TTE---TGVVTINIDHSLECSVGRLAPGMRIKIQGEDGQQLGVNQTGEVLIDIGLKWEGYLSNPE 396

  Fly   405 ET-RQIQDSENWIHTGDLGYVDKDGYLFVIDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEACVF 468
            :| ..:||  .||:.|||||.|:|..|:::||.||:|||::..|:|:|||.:|||:|.|...||.
  Fly   397 DTATTLQD--GWINLGDLGYFDEDNNLYLVDRKKDLLKYKSKHYWPNEIEQIIAELPEVEHVCVV 459

  Fly   469 GIWDPVNGDEAAASLVKKPGTQLEAQDVVEYVRKRITAKFKQLNGGALIVDQIVRSGNRKTNRSA 533
            |:.|...||.|.|.::||.|.::..|.|:::|.:|:...:||||.|.:.||:..::.|.|..||.
  Fly   460 GVRDARYGDAAGALIIKKEGAEIADQKVIDHVAQRVVVDYKQLNAGVIFVDKFPKNANGKVMRSL 524

  Fly   534 VKEHFLK 540
            .:|.|.|
  Fly   525 AREVFEK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	177/509 (35%)
		AFD_class_I	55..530	CDD:302604	166/477 (35%)
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	177/515 (34%)
		Firefly_Luc_like	49..521	CDD:213279	166/477 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471308
Domainoid	1	1.000	215	1.000	Domainoid score	I5876
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26958
OrthoDB	1	1.010	-	-		D24284at7147
OrthoFinder	1	1.000	-	-		FOG0004528
OrthoInspector	1	1.000	-	-		mtm9651
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X778
	10	9.860