Protein Alignment CG18586 and ACSL6

DIOPT Version :10

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_056071.2
• Gene: ACSL6 / 23305
• HGNCID: 16496
• Length: 722
• Species: Homo sapiens
• Alignment Length: 589
• Identity: 127/589 - (21%)
• Similarity: 206/589 - (34%)
• Gaps: 184/589 - (31%)

  Fly    89 TD-IVGVMGRHTTHQSAVAYACFFNGTPLHALHNAYEEACIAKLFG--------ITKPR------ 138
            || .:||..::......|..||:.....:..|::......|..:..        :.||:
Human   171 TDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLL 235

  Fly   139 -------------LIFCDGDEYEKVKSATKDLQVTIVTMR--------NHPRGSVRIQDVLTTPV 182
                         :|..|..| |.:|...:...|.|.:|:        ||           ..||
Human   236 EHVERKETPGLKLIILMDPFE-EALKERGQKCGVVIKSMQAVEDCGQENH-----------QAPV 288

  Fly   183 MQNFQPLRLKDGIDHTLAILSSSGTSGFPKAVTISNSHKIIVDYMA-INNSNIQYTSSTLD---- 242
            ..  ||       |....:..:|||:|.||...:::.: ::.|:.. :..:..|:..:..|
Human   289 PP--QP-------DDLSIVCFTSGTTGNPKGAMLTHGN-VVADFSGFLKVTESQWAPTCADVHIS 343

  Fly   243 ----------------WCSGLSMAITSGVFSTTSIIADCDFDPGLFCRAIGKYRISMVLLSSSYL 291
                            :|.|..:....|   ...:::|   |....|..|  :.:...||:..|.
Human   344 YLPLAHMFERMVQSVVYCHGGRVGFFQG---DIRLLSD---DMKALCPTI--FPVVPRLLNRMYD 400

  Fly   292 AIF--ANCP------EF----ESADLSS------------------------LNYVIFGGSSCSL 320
            .||  ||.|      ||    :.|::.|                        :..::.|.:..|.
Human   401 KIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASP 465

  Fly   321 EVQRKVRSRLSHDCLNFC-----YGLTELNSAGSVNLNFDEKPNSVGRAIRGIKIKVIDEQ---- 376
            .|...:|:.|.      |     ||.||..:..:.....|.....||..:....||::|.:
Human   466 TVLGFLRAALG------CQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNY 524

  Fly   377 ----GEAQEPNVVGEICFHNSQKWAGYYKNPDETRQIQDSENWIHTGDLGYVDKDGYLFVIDRLK 437
                ||       ||||......:.||.|:||.|::..||:.|:||||:|.....|.|.:|||.|
Human   525 WACKGE-------GEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKK 582

  Fly   438 DMLKYQNIMYY-PSEIENV-IAEMP--------NVLEACVFGIWDPVNGDEAAASLVKKPGTQ-- 490
            .:.|.....|. |.:|||: |...|        :.|:|.:.||..|  ..|...|..:|.|.:
Human   583 HIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVP--DPEVMPSWAQKRGIEGT 645

  Fly   491 --------------LEAQDVVEYVRKRITAKFKQLNGGALIVDQI-VRSG----NRKTNRSAVKE 536
                          ||  |:|...::.....|:|:....:..|.. |::|    ..|..|..::|
Human   646 YADLCTNKDLKKAILE--DMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELRE 708

  Fly   537 HFLK 540
            :|.|
Human   709 YFKK 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	Firefly_Luc_like	55..530	CDD:341237	123/577 (21%)
ACSL6	NP_056071.2	LC-FACS_euk	141..719	CDD:341250	127/589 (22%)