Protein Alignment CG18586 and ACSF3

DIOPT Version :10

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_777577.2
• Gene: ACSF3 / 197322
• HGNCID: 27288
• Length: 576
• Species: Homo sapiens
• Alignment Length: 594
• Identity: 124/594 - (20%)
• Similarity: 224/594 - (37%)
• Gaps: 140/594 - (23%)

  Fly    25 SGREAPSLFSPNLSIGEIIFGDMVNNPKLIAQISITEDIVLTREDLHMNAMRVASYMRNMGLGQ- 88
            |.|.|| :|:..|:     |||         :|::.        |.|........|.|::.|.|
Human    40 SDRSAP-VFTRALA-----FGD---------RIALV--------DQHGRHTYRELYSRSLRLSQE 81

  Fly    89 -TDIVGVMGRHTTHQSAVAYAC-------------FFNG---TPLHALHNAYEEACIAKLFGITK 136
             ..:.|.:| ....:..|::.|             :.:|   .||:..|.|      |:|
Human    82 ICRLCGCVG-GDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA------AQL----- 134

  Fly   137 PRLIFCD--------GDEY-EKVKSATKDLQVTIVTMRNHP---RGSVRIQDVLTTPVMQNFQPL 189
             ..:.||        ..|| |.:....:.|.|.::.:.  |   .|:|  ::....||.:  |..
Human   135 -EYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLT--PAIYTGAV--EEPAEVPVPE--QGW 192

  Fly   190 RLKDGIDHTLAILSSSGTSGFPKAV--TISNSHKII---VDYMAINNSNIQYTSSTLDWCSGLSM 249
            |.|..:     |:.:|||:|.||.|  |..|...::   |...|....::......|....|:..
Human   193 RNKGAM-----IIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVN 252

  Fly   250 AITSGVFSTTSIIADCDFDPGLFCRAIGKYRISMVLLSSS------YLA---IFANCPEFESADL 305
            |:...::...:.:...:|.|         .::....|||.      ::|   |:....|:.....
Human   253 ALLCPLWVGATCVMMPEFSP---------QQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHF 308

  Fly   306 S--------------SLNYVIFGGSSCSLEVQRKVRSRLSHDCLNFCYGLTELNSAGSVNLNFDE 356
            :              .:..::.|.::..|.|..|.::...|..|. .||:||:..|.|..|....
Human   309 TQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLE-RYGMTEIGMALSGPLTTAV 372

  Fly   357 K-PNSVGRAIRGIKIKVI-----------------DEQGEAQEPNV---VGEICFHNSQKWAGYY 400
            : |.|||..:.|::::::                 ||:|....|..   .||:.......:..|:
Human   373 RLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYW 437

  Fly   401 KNPDETRQIQDSENWIHTGDLGYVDKDGYLFVIDRLK-DMLKYQNIMYYPSEIENVIAEMPNVLE 464
            ..|:||:.....:.|..|||. .|.|||..::..|.. |::|.........|:|..:...|::.:
Human   438 NKPEETKSAFTLDGWFKTGDT-VVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITD 501

  Fly   465 ACVFGIWDPVNGDEAAASLVKKPGTQLEAQDVVEYVRKRITAKFKQLNGGALIVDQIVRSGNRKT 529
            ..|.|:.|...|....|.:..:.|..|..:::.|:.| .:.|.: .:....::|::|.|:...|.
Human   502 VAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWAR-NVLAPY-AVPSELVLVEEIPRNQMGKI 564

  Fly   530 NRSAVKEHF 538
            ::.|:..||
Human   565 DKKALIRHF 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	Firefly_Luc_like	55..530	CDD:341237	112/554 (20%)
ACSF3	NP_777577.2	MCS	55..571	CDD:341264	114/569 (20%)