DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18586 and Acsbg1

DIOPT Version :9

Sequence 1:	NP_647993.2	Gene:	CG18586 / 38659	FlyBaseID:	FBgn0035642	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_599216.1	Gene:	Acsbg1 / 171410	RGDID:	708557	Length:	721	Species:	Rattus norvegicus

Alignment Length:	574	Identity:	116/574 - (20%)
Similarity:	215/574 - (37%)	Gaps:	151/574 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 HMNAMRVASYMRNMGLGQTDIVGVMGRHTTHQSAVAYACFFNGTPLHALH-NAYEEAC--IAKLF 132
            ::.|.:||.....:||.:...|.::|.::......|....|.|..:..:: .:..|||  ||.
  Rat   136 YLIARKVAKGFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAH-- 198

  Fly   133 GITKPRLIFCDGD-EYEKVKSATKD---LQVTIVTMRNHPRGSVRIQDVLTTPVMQNFQPLRLKD 193
             ..:..:|..|.. :.||:....||   |:..::.....|:....:..:.....:....|....|
  Rat   199 -DCRANVIVVDTQKQLEKILKIWKDLPHLKAVVIYQEPPPKKMANVYTMEELIELGQEVPEEALD 262

  Fly   194 GIDHT------LAILSSSGTSGFPKAVTISNSH---------------------KIIVDYMAINN 231
            .|..|      ..::.:|||:|.||.|.:|..:                     :::|.|:.:::
  Rat   263 AIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIQPAEVQQEVVVSYLPLSH 327

  Fly   232 SNIQYTSSTLDWCSGLSMAITSGVFSTTSIIADCDFDPGLFCRAIGKY----------------- 279
                ..:...|..:|:.       :......||.|...|.....:.:.
  Rat   328 ----IAAQIYDLWTGIQ-------WGAQVCFADPDALKGTLVNTLREVEPTSHMGVPRVWEKIME 381

  Fly   280 RISMVLLSSSY----LAIFA---------NCPEFESADLSS--LNYVI----------------- 312
            ||..|...|.:    :.::|         .||..:....:|  .:|::
  Rat   382 RIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPSNDLKPFTSRLADYLVLARVRQALGFAKCQKNF 446

  Fly   313 FGGSSCSLEVQR-----KVRSRLSHDCLNFCYGLTELNSAGSVNLNFDEKPNSVGRAIRGIKIKV 372
            :|.:..:.|.||     .:|       |...|||:|......::..::.:..|.||.:.|.::|:
  Rat   447 YGAAPMTAETQRFFLGLNIR-------LYAGYGLSESTGPHFMSSPYNYRLYSSGRVVPGCRVKL 504

  Fly   373 IDEQGEAQEPNVVGEICFHNSQKWAGYYKNPDETRQIQDSENWIHTGDLGYVDKDGYLFVIDRLK 437
            ::     |:.:.:||||......:.||....|:|.:..|||.|:||||:|.:|.||:|::..|||
  Rat   505 VN-----QDADGIGEICLWGRTIFMGYLNMEDKTHEAIDSEGWLHTGDMGRLDDDGFLYITGRLK 564

  Fly   438 DML---KYQNIMYYPSEIENVIAEMPNVLEACVFG-------------------IWDPV-NGDEA 479
            :::   ..:|:...|.| |.|..|:|.:..|.:.|                   ..:|. |..|.
  Rat   565 ELIITAGGENVPPVPIE-EAVKMELPIISSAMLIGDQRKFLSMLLTLKCTLNPETSEPTDNLTEQ 628

  Fly   480 AASLVKKPGTQLEAQDVVEYVRKRITAKFKQLNGGALIVDQIVRSGNRKTNRSA 533
            |....::.|:  :|..|.|.|.::..|           |.|.:..|.::.|.:|
  Rat   629 AVEFCQRVGS--KASTVSEIVGQKDEA-----------VYQAIHEGIQRVNANA 669

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	116/574 (20%)
CG18586	NP_647993.2	AFD_class_I	55..530	CDD:302604	114/569 (20%)
Acsbg1	NP_599216.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64
Acsbg1	NP_599216.1	ACSBG_like	122..716	CDD:341256	116/574 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342864
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930