Protein Alignment CG18586 and ACSM1

DIOPT Version :9

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001305819.1
• Gene: ACSM1 / 116285
• HGNCID: 18049
• Length: 577
• Species: Homo sapiens
• Alignment Length: 540
• Identity: 123/540 - (22%)
• Similarity: 209/540 - (38%)
• Gaps: 101/540 - (18%)

  Fly    21 LKIWSGREAPSLFSPNLSI----GEIIFGDMVNNPKLIAQISITEDIVLTREDLHMNAMRVAS-Y 80
            |..|:.:|......||.:.    |:   ||.|       :.|..|...|||        |||: :
Human    56 LDYWAQKEKEGKRGPNPAFWWVNGQ---GDEV-------KWSFREMGDLTR--------RVANVF 102

  Fly    81 MRNMGLGQTDIVGVMGRHTTHQSAVAYAC------FFNGTPLHALHNAYEEACIAKLFGITKPRL 139
            .:..||.|.|.:.:|.........||..|      |...|.|....:......::|..||.   .
Human   103 TQTCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIV---T 164

  Fly   140 IFCDGDEYEKVKSATKDLQVTIVTMRNHPRGSVRIQDVLTTPVMQNFQPLRLKDGIDHT------ 198
            |.....|.:.:.|....|:..::...:...|.:            :|:.|......:||
Human   165 IDALASEVDSIASQCPSLKTKLLVSDHSREGWL------------DFRSLVKSASPEHTCVKSKT 217

  Fly   199 ---LAILSSSGTSGFPKAVTISNSHKIIVDYMAINNSNIQ-YTSSTLDWCSGLSMAITSGVFSTT 259
               :.|..:|||:||||..  .:||.:.:......:..:: ..:|.:.||...|..|.:.:::..
Human   218 LDPMVIFFTSGTTGFPKMA--KHSHGLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLV 280

  Fly   260 S-IIADC--------DFDPGLFCRAIGKYRISMVL-LSSSYLAIFANCPEFESADLSSLNYVIFG 314
            . ..|.|        .||..:..:.:.||.|:... :||.|..|...  :|.|....:|.:...|
Human   281 EPWTAGCTVFIHHLPQFDTKVIIQTLLKYPINHFWGVSSIYRMILQQ--DFTSIRFPALEHCYTG 343

  Fly   315 GSSCSLEVQRKVRSRLSHDCLNFCYGLTELNSAGSVNLNFDEKPNSVGRAIRGIKIKVIDEQGEA 379
            |.....:.|.:.:.|... .|...||.:|.....:.......||..:|:|.....::|||::|..
Human   344 GEVVLPKDQEEWKRRTGL-LLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVIDDKGSI 407

  Fly   380 QEPNVVGEI--------------CFHNSQKWAGYYKNPDETRQIQDSENWIHTGDLGYVDKDGYL 430
            ..||..|.|              |         |..:|::|.:::..: :.:|||.|.:|::||:
Human   408 LPPNTEGNIGIRIKPVRPVSLFMC---------YEGDPEKTAKVECGD-FYNTGDRGKMDEEGYI 462

  Fly   431 FVIDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEACVFGIWDPVNGDEAAASLVKKPGTQLEAQD 495
            ..:.|..|::........|:|:|:.:.|.|.|.|:.|.|..||:.|:...|.:|..|  |..:.|
Human   463 CFLGRSDDIINASGYRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTP--QFLSHD 525

  Fly   496 VVEYVR------KRITAKFK 509
            ..:..:      |.:||.:|
Human   526 KDQLTKELQQHVKSVTAPYK 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	120/526 (23%)
		AFD_class_I	55..530	CDD:302604	114/502 (23%)
ACSM1	NP_001305819.1	MACS_euk	45..574	CDD:341251	123/540 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920