DRSC/TRiP Functional Genomics Resources

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Protein Alignment vn and celsr2

DIOPT Version :9

Sequence 1:NP_523942.2 Gene:vn / 38657 FlyBaseID:FBgn0003984 Length:623 Species:Drosophila melanogaster
Sequence 2:NP_001074046.1 Gene:celsr2 / 560426 ZFINID:ZDB-GENE-070122-2 Length:2941 Species:Danio rerio


Alignment Length:286 Identity:54/286 - (18%)
Similarity:89/286 - (31%) Gaps:70/286 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   374 RLQFALSNSSGECDIYRERLMPRGMLRSGNDLQQASDIS-------YMMFVQQTNPGNFTIL--- 428
            |...||......|    |::|...:...|..|...:|::       :|.|:.:|.....|::   
Zfish  1665 RCDCALGFGGRNC----EKVMSNPLRLQGKGLLWWADLASVMTPPWHMEFMFRTRQPTATVMHMS 1725

  Fly   429 -GQPMRVTHLVVEA-VETAVSENYTQNAEVTKIFSKPSKAIIKHGKKLRIVCEVSGQPPPKVT-- 489
             ||....|..:.|. |.|:|     |..| ..:.|:.....:..|:...:..|:.|.....||  
Zfish  1726 SGQQHNFTIQLREGFVVTSV-----QRGE-DSVVSRVDDVTVSDGQWHHVSLELKGPATGGVTAT 1784

  Fly   490 ------WFKDEKSINRKRNIYQFK--------HHKRRSELIVRSFNSSSDAGRYECRAKNKASKA 540
                  .:.....::.|....:.|        ..:.|   ::..|.......|....:...|..:
Zfish  1785 LSLDYGLYTSSMDLDSKLKGVRLKTLSVGGVSDGRNR---VIGGFRGCIQGLRIGGDSSTPAFPS 1846

  Fly   541 IAKRRIMIKASPVHFPT---------------DRSASGIPCNFDY-------------CFHNGTC 577
            :.:.|::...|....|.               |..|....|:..|             |.|...|
Zfish  1847 MPQARVLNVESGCSLPNTCGSNPCPAHSDCKDDWDAHSCRCHTGYYGNSCTDACALNPCEHQSAC 1911

  Fly   578 -RMIPDINEVYCRCPTEYFGNRCENK 602
             |.....:...|.||:.|||..||.|
Zfish  1912 SRRSSSAHGYTCSCPSNYFGQYCEKK 1937

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
vnNP_523942.2 IGc2 471..538 CDD:197706 10/82 (12%)
EGF 566..598 CDD:278437 12/45 (27%)
celsr2NP_001074046.1 Cadherin_repeat 248..347 CDD:206637
Cadherin_repeat 356..455 CDD:206637
Cadherin_repeat 464..561 CDD:206637
Cadherin_repeat 569..666 CDD:206637
Cadherin_repeat 675..768 CDD:206637
Cadherin_repeat 776..871 CDD:206637
Cadherin_repeat 880..977 CDD:206637
Cadherin_repeat 985..1079 CDD:206637
Cadherin_repeat 1099..1180 CDD:206637
EGF_CA 1356..1391 CDD:238011
EGF_CA 1399..1432 CDD:238011
LamG 1436..>1529 CDD:238058
EGF_CA 1644..1678 CDD:238011 4/16 (25%)
Laminin_G_2 1712..1837 CDD:280389 22/133 (17%)
EGF_CA 1863..1897 CDD:238011 4/33 (12%)
TNFRSF 1924..1993 CDD:304602 8/14 (57%)
EGF_Lam 1992..2037 CDD:214543
HormR 2041..2102 CDD:214468
GAIN 2120..2358 CDD:293098
GPS 2386..2439 CDD:197639
7tm_4 2445..2677 CDD:304433
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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