DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Myt1 and WEE1

Sequence 1:NP_647987.2 Gene:Myt1 FlyBaseID:FBgn0040298 Length:533 Species:Drosophila melanogaster
Sequence 2:NP_003381.1 Gene:WEE1 HGNCID:12761 Length:646 Species:Homo sapiens

Alignment Length:378 Identity:113/379 (30%)
Similarity:170/379 (45%) Gaps:48/379 (13%)


  Fly    26 NSNRFRPPKYKTRGYVAVDNNNLNRSQSLGSCSTNSSQIAHAISFRDAGCSD----SSTLPSSPV 86
            |.|.|.|           |:..|:.|   |.|........:.....|...||    ..|.|:..:
Human   234 NINPFTP-----------DSLLLHSS---GQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRI 284

  Fly    87 QAELSTLSLSHFEQCFERLAKLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQYRAERLEEVR 151
            ....|.:. |.:...|..|.|:|.|.||.||:...|.||.:||:|.||:...|.......|.||.
Human   285 TITESNMK-SRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVY 348

  Fly   152 RYEEFSGHENCIRFIRAWEQYDRLYMQMELCR-ESLEQYLLRCQRI----PEERIWHILLDLLRG 211
            .:.....|.:.:|:..||.:.|.:.:|.|.|. .||...:....||    .|..:..:||.:.||
Human   349 AHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRG 413

  Fly   212 LKSLHDRNLIHLDIKLDNVLI------------GEDDETC------KLADFGLVIDVDRANSHHA 258
            |:.:|..:|:|:|||..|:.|            |::|:..      |:.|.|   .|.|.:|...
Human   414 LRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLG---HVTRISSPQV 475

  Fly   259 TEGDSRYMAPEILQGHFS--KAADIFSLGIAMLELACYMDLPSNGPLWHELRHGILPEEFINKIS 321
            .|||||::|.|:||.:::  ..||||:|.:.::..|....||.||..|||:|.|.|| .....:|
Human   476 EEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLP-RIPQVLS 539

  Fly   322 LELQSVIKSMMKPDPAQRPTAEQLLSHPKLQYLQKKRKSLMNFSMLSRSFRRS 374
            .|...::|.|:.|||.:||:|..|:.|..|....:|....:...:.:..|:.|
Human   540 QEFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNS 592

Known Domains:


GeneSequenceDomainRegion External IDIdentity
Myt1NP_647987.2 PKc_Myt1 100..349 CDD:270952 93/274 (34%)
Pkinase 102..349 CDD:278497 93/272 (34%)
WEE1NP_003381.1 PTKc_Wee1a 293..568 CDD:271040 94/279 (34%)
Pkinase 299..569 CDD:278497 93/274 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_KOG0601
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 D1063695at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 avgDist Average_Evolutionary_Distance R1671
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.940

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