Protein Alignment Myt1 and Pkmyt1

DIOPT Version :10

• Sequence 1: NP_647987.2
• Gene: Myt1 / 38649
• FlyBaseID: FBgn0040298
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: XP_006524373.1
• Gene: Pkmyt1 / 268930
• MGIID: 2137630
• Length: 539
• Species: Mus musculus
• Alignment Length: 483
• Identity: 174/483 - (36%)
• Similarity: 245/483 - (50%)
• Gaps: 75/483 - (15%)

  Fly    28 NRFRPPKYKTRGYVAVDNNNLNRSQSLGSCSTNSSQIAHAISFRDAGCSDSSTLPS---SPVQAE 89
            :|..||:...:|.:.|  :.|...::.|.......:::..       |..|..|.|   .|.:.|
Mouse    88 SRSLPPRPPAKGCIPV--SRLFPPRTPGWHQPQPRRVSFL-------CETSEPLQSPGYDPSRPE 143

  Fly    90 LSTLSLSHFEQCFERLAKLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQYRAERLEEVRRYE 154
                  |.|:|.|:||::||.||:||||:||.:.||:|||||.....|||.:.|..:|.||..:|
Mouse   144 ------SFFQQNFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRYMSPFRGPKDRTRKLAEVGGHE 202

  Fly   155 EFSGHENCIRFIRAWEQYDRLYMQMELCRESLEQYLLRCQ----RIPEERIWHILLDLLRGLKSL 215
            :...|.:|:|..||||:...||:|.|||..||:|:   |:    .:||.::|..|.|:|..|..|
Mouse   203 KVGQHPHCVRLERAWEEGGILYLQTELCGPSLQQH---CEAWGASLPEAQVWGYLRDILLALDHL 264

  Fly   216 HDRNLIHLDIKLDNVLIGEDDETCKLADFGLVIDVDRANSHHATEGDSRYMAPEILQGHFSKAAD 280
            |.:.|:|||:|..|:.:|.... |||.||||::::..|.:..|.|||.||||||:|||.:..|||
Mouse   265 HSQGLVHLDVKPANIFLGPRGR-CKLGDFGLLVELGSAGAGEAQEGDPRYMAPELLQGSYGTAAD 328

  Fly   281 IFSLGIAMLELACYMDLPSNGPLWHELRHGILPEEFINKISLELQSVIKSMMKPDPAQRPTAEQL 345
            :||||:.:||:||.|:||..|..|.:||.|.||.||...:|.||:||:..|::|||..|.|||.|
Mouse   329 VFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLAMMLEPDPQLRATAEAL 393

  Fly   346 LSHPKLQYLQKKRKSL---MNFSMLSRSFRRSRRAVWGRMCNWKTAAFRYLLYFLEVLH-LCKPI 406
            |:.|.|:  |.:..::   |....|||.:     |:|        .|...||.:|  .| |..|.
Mouse   394 LALPMLR--QPRPWNVLWYMAAEALSRGW-----ALW--------QALVTLLCWL--WHGLVHPA 441

  Fly   407 TASQPNINIVPSSPSSKGVPLVPQVEFQLVGSTPIANRDCYASDFLSGEDPLDLSNQGSPNVI-- 469
            :..||           .|.|..|.      ||.|.:  ....|...|..|...:....||..:
Mouse   442 SWLQP-----------PGPPATPP------GSPPCS--PLLDSTLSSSWDNDSIGPSLSPETVLS 487

  Fly   470 -----NSTPLNTNQGKSRLDLLKNNVDS 492
                 .|||......:..|||  .:|||
Mouse   488 RITRRTSTPRGRYIPRDALDL--TDVDS 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	121/252 (48%)
Pkmyt1	XP_006524373.1	PKc_Myt1	148..397	CDD:270952	121/252 (48%)