Protein Alignment Usp47 and faf

DIOPT Version :10

• Sequence 1: NP_523937.2
• Gene: Usp47 / 38644
• FlyBaseID: FBgn0016756
• Length: 1556
• Species: Drosophila melanogaster
• Sequence 2: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Alignment Length: 1138
• Identity: 238/1138 - (20%)
• Similarity: 382/1138 - (33%)
• Gaps: 357/1138 - (31%)

  Fly   358 DELRAWQRVNTTGADFVSSATTETEAEARQASLGPRGYVGLVNQAMTCYLNSLLQALFMTPEFRN 422
            |.||.|..:...||                  ...:|:.||.|...|||:||:||.|:|.|..|.
  Fly  1648 DPLREWDYLPPVGA------------------RPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRV 1694

  Fly   423 ALYR---------WEFDNDNE-----------------------------------AKN----IP 439
            .:.|         .:|..|::                                   .||    |.
  Fly  1695 GILRAHGAATTDGEDFSGDSDLTGGGLGSALFSGPASALVSLPSSSSTIEDGLHDVRKNYHVVIL 1759

  Fly   440 YQLQKLFLNLQTSPKAAVETTDLTRSFG--WDSTEAWQQHDIQELCRVMFDALEHKFKNTKQANL 502
            ..:|.:|.:|..|.........|...|.  .:.....:|.|..|....:.::|:...|...|..|
  Fly  1760 KHVQAIFAHLGHSALQYYVPRGLWTHFKLLGEPVNLREQQDAVEFFMSLLESLDEGLKALGQPQL 1824

  Fly   503 ISNLYEGKMNDYVKCLECNTEKTREDTFLDIPLPVRPFGSSSAYGSIEEALRAFVQPETLDGNNQ 567
            ::....|..:|...|.||....::|:.|....:.:|      .:.|:.|:|..:|:.|.|:|.:.
  Fly  1825 MNATLGGSFSDQKICQECPHRYSKEEPFSVFSVDIR------NHSSLTESLEQYVKGELLEGADA 1883

  Fly   568 YLCEKCKKKCDAHKGLHFKSFPYILTLHLKRFDFDYQTMHRIKLNDRVTFPQTLNLNTFINRSGN 632
            |.|:||.||....|.:..|..|.:|.:.||||::||:.:..||.||...||:.|::..:
  Fly  1884 YHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPY------ 1942

  Fly   633 SGEQNSQLNGTVDDCSTADSGSAMEDDNLSSGVVTTASSSQHENDLNDEDEGIDMSSSTSKSAKQ 697
                      ||...:..:.......||..:.|.||.
  Fly  1943 ----------TVSGLAKLEGEVVEVGDNCQTNVETTK---------------------------- 1969

  Fly   698 GSGPYLYELFAIMIHSGSASGGHYYAYI--KDFDNN--EWFCFNDQNVTSITQEDIQ----RSFG 754
                  |||..|::|||.||||||::||  |:..|.  :|:.|:|..||.....:.:    ..||
  Fly  1970 ------YELTGIVVHSGQASGGHYFSYILSKNPANGKCQWYKFDDGEVTECKMHEDEEMKAECFG 2028

  Fly   755 GPNGSYYSSAYTSST------------NAYMLMYRQVDAKRNELVAKVADF----PEHIKTLLPK 803
               |.|....|.::.            |||||.|.:.|....:....|...    ..::...|||
  Fly  2029 ---GEYMGETYDNNLKRMQYRRQKRWWNAYMLFYTRCDQTPVQYEPSVEQLSLAESRNMVLPLPK 2090

  Fly   804 LHSEEETRVSRLGRHITVTDLALPDLYKPRVYFYNPSLKKMKITRVYVSQSFNINLVLMSAYE-- 866
                   .:.|..||..:..|....::.  |.|:| .:||:....:..::|   |.:..:|.|
  Fly  2091 -------PIERSVRHQNIRFLHSRSIFS--VEFFN-FIKKLVSCNLLSARS---NKITPAAEELS 2142

  Fly   867 MLNVEQFAPLSRCRLVAYNSSMDTIIQSLESCTDPALTELRAAQNYSLDFLLEYRAEDQEFEVYP 931
            :|.|:          :|......|..::.:|...|.:....|..::.....|..:.......:.|
  Fly  2143 LLGVQ----------LASQFLFHTGFRTKKSLRGPVMEWYDALSHHIRSSALVRKWFANHALLSP 2197

  Fly   932 PNGITWYVFKV---DLSTMAM------------DGPFLVYSAAR-------------EREASDVL 968
            |:.:..|:...   |:.|:.:            |.|...|..|.             :.||:|..
  Fly  2198 PSRLGEYILMAPSPDVRTVFVKLVVFFCHFAINDEPLTGYDGANLCEQVLISVLRLLKSEAADYG 2262

  Fly   969 RR--------SIALRLHISEQQFLLATVRATVPKAF--VSYDPHPTPEALQHLQNMANTQFKSIT 1023
            :.        |:.:.|...|:|.||   |..||..|  |:.|..|.|               :|.
  Fly  2263 KHLPHYFSLFSMYVGLGTREKQQLL---RLNVPLQFIQVALDDGPGP---------------AIK 2309

  Fly  1024 YFYLNVPNTDAATLEMLGVPTVESVECASGGDVVDAAMMNGVAPGHMSSSNDYDWRRYKRDLVEP 1088
            |.|............::....| |.:|.|                  |:.|       .|.|..|
  Fly  2310 YQYPEFSKLHQVVSHLIRCSDV-SEKCQS------------------SNQN-------ARPLSNP 2348

  Fly  1089 MSQPSPSHGHESNSEDSSLSDG------DRT-----LVETDNMAHRGGGDSQVSSTSHSPQLSSP 1142
            ...|:.:|     .|.:.||..      :||     ::|..|:...|....|..|. .:|..|
  Fly  2349 FKDPNVAH-----EELTPLSTECMDLLFNRTGYIKKVIEDTNVGDEGLKLLQYCSW-ENPHFS-- 2405

  Fly  1143 EDEAASHDAMMRV-HAYCNGNGSYAAADVVDPLLLPTSTNHFFYATKVECVDVVGTGSSSGHQSD 1206
              .|...:.:.:. .|||:....:... :::.||:..|..|.    ::.       .:.:|...:
  Fly  2406 --RAVLTELLWQCGFAYCHDMRHHTDL-LLNILLIDDSWQHH----RIH-------NALNGVAEE 2456

  Fly  1207 EEAQLRKPTRAYKLLVGTHMRMGAFK--KHIEQLI-QVPAAHFKLQRKHDNN------------- 1255
            .|..|....||     .||.:..|::  |.:.||. :.|.|   ||..|.|:
  Fly  2457 REGLLETIQRA-----KTHYQKRAYQIIKCLTQLFHKSPIA---LQMLHTNSNITRHWSIAVEWL 2513

  Fly  1256 ------------------------LSNNQNNSLVHLIEGETLTVELGKTLEPDEFKAKIHFLRLA 1296
                                    .::|.|..::...:....|..:...|.|||...|      .
  Fly  2514 QGELDRQRGIGCQYNSYSWSPPAQSNDNTNGYMLERSQSAKNTWSMAFELCPDEVSEK------T 2572

  Fly  1297 DIDNETSKLPCVCEWVYNANTTAEQAKKELVAK 1329
            |.:||.           |..|..::.|.|.||:
  Fly  2573 DENNEP-----------NLETNMDENKSEPVAQ 2594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp47	NP_523937.2	DUF4045	<122..249	CDD:433066
		peptidase_C19C	394..780	CDD:239124	112/455 (25%)
		USP47_C	1300..1534	CDD:466158	8/30 (27%)
faf	NP_524612.2	Ubl1_cv_Nsp3_N-like	<994..1060	CDD:475130
		peptidase_C19C	1666..2064	CDD:239124	112/456 (25%)
		DUF3517	2198..2566	CDD:463438	80/441 (18%)