Protein Alignment Usp47 and Usp2

DIOPT Version :10

• Sequence 1: NP_523937.2
• Gene: Usp47 / 38644
• FlyBaseID: FBgn0016756
• Length: 1556
• Species: Drosophila melanogaster
• Sequence 2: NP_001285528.1
• Gene: Usp2 / 33132
• FlyBaseID: FBgn0031187
• Length: 950
• Species: Drosophila melanogaster
• Alignment Length: 728
• Identity: 160/728 - (21%)
• Similarity: 257/728 - (35%)
• Gaps: 194/728 - (26%)

  Fly   113 VKKVMKSDGEKAKSPATGE--------------KKKRVVGEKTKKKPASGSSSPSKAKTTSE-DS 162
            ::|.....|:|.::|.:|.              .:..|.........|.||||..:.:.:|: |:
  Fly   354 IEKFNNLSGQKRQNPGSGSGIGPGSATASGLGGGRLSVASRSNHGSQAGGSSSNLQQRYSSDLDN 418

  Fly   163 LAKTSISSESSPEKTSKIKTTAAKISKPGSEKAPRASPEECPELSTEINSKNTSSESPVAKKTAK 227
            :...:..|.|......:...|...:|.|.:..:         ||...|:.....:.:.:.:.|:|
  Fly   419 IRVAAGYSSSLTRAAYRTTATMNSVSTPVAVTS---------ELGGPISGDGGETATAMGQPTSK 474

  Fly   228 VTSKPTLELLSPIKPSSPIKELDCEPV---DTLSKQQLSEQLQLYPQGRNLISPVDDAPSDLFIS 289
            ||.:.......||         :|:.|   :..||...:.............:|...:.|.:.::
  Fly   475 VTVRGAHSNRQPI---------ECDSVVLTNKASKDATTAATPTVATATATHTPATSSVSTVTVT 530

  Fly   290 DAEQLS-DDDLALGASASP---TMLGPGYDYGAPTGDSDVEGVTGVTDPSTIGTDDGTYPALSNF 350
            .|...| .|.::...:.||   |:...|      ||.|..  ...|..|.|        |..|.:
  Fly   531 AAAPNSASDSVSRSLARSPISSTLARSG------TGSSST--ARSVLPPMT--------PTSSRY 579

  Fly   351 YRRKYGGDELRAWQRVNTTGADFVSSATTETEAEARQASLG----PRGYVGLVNQAMTCYLNSLL 411
            :.|..|...    ..:.|:.|...||....::...:.||..    ..|..||.|...||::||::
  Fly   580 WDRDSGTSR----SSIGTSSALNSSSLKHNSDDGYKTASSSRDEKSEGLCGLRNIGNTCFMNSVI 640

  Fly   412 QALFMTPEFRNALYRWEFDNDNEAKN--IPYQLQKLFLNLQTSPKAAVETTDLTRSFGWDSTE-- 472
            |.|..|.|....|...........|:  |.::..||...:.|:....|...:|.|:|   ||:
  Fly   641 QCLSHTQELTRFLRSHHGSRSLSTKDQQILHEFAKLIQEMWTANVHTVTPMELKRAF---STKHR 702

  Fly   473 ---AWQQHDIQELCRVMFDAL---------------EHKFKNTKQA------------NLISNLY 507
               .:.|.|.||..|...|:|               :....:.|:|            :|:.:|:
  Fly   703 MYSDYNQQDAQEFLRFFLDSLHSALNSGVKGETLNIDDNLSDNKKADLTWEWYTRHENSLVRDLF 767

  Fly   508 EGKMNDYVKCLECNTEKTREDTF--LDIPLPVRPFGSSSAYGSIEEALRAFVQPETLDGNNQYLC 570
            .|::...:||..|.......|.|  |.:|||      ||:...:|..|..|::.|.|||:....|
  Fly   768 VGQLKSTLKCTTCGNTSVTFDPFWDLSVPLP------SSSRCKLEACLDLFIREEVLDGDEMPTC 826

  Fly   571 EKCKKKCDAHKGLHFKSFPYILTLHLKRFDFDYQTMHRIKLNDRVTFPQTLNLNTFINRSGNSGE 635
            .|||.:....|....:.||..|.:|||||.   :|... ||::.|.||
  Fly   827 AKCKTRRKCTKSFTIQRFPKYLVIHLKRFS---ETRWS-KLSNIVEFP----------------- 870

  Fly   636 QNSQLNGTVDDCSTADSGSAMEDDNLSSGVVTTASSSQHENDLNDEDEGIDMSSSTSKSAKQGSG 700
                         |:||                        :||....|.:.:|:..
  Fly   871 -------------TSDS------------------------ELNMGSYGANSNSNVH-------- 890

  Fly   701 PYLYELFAIMIHSGSASGGHYYAYIKDFDNNEWFCFNDQNVTSITQEDIQRSFGGPNGSYYSSAY 765
               |.|:||..|.||.:||||.|..|...:.:|..|||..|:....|:                :
  Fly   891 ---YSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSDALSEN----------------H 936

  Fly   766 TSSTNAYMLMYRQ 778
            ..|::||:|.|.:
  Fly   937 LVSSSAYILFYER 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp47	NP_523937.2	DUF4045	<122..249	CDD:433066	25/141 (18%)
		peptidase_C19C	394..780	CDD:239124	104/421 (25%)
		USP47_C	1300..1534	CDD:466158
Usp2	NP_001285528.1	UBP12	<620..>800	CDD:227847	45/188 (24%)
		Peptidase_C19R	626..948	CDD:239139	102/415 (25%)