Protein Alignment Sse and ESP1

DIOPT Version :9

• Sequence 1: NP_523935.1
• Gene: Sse / 38640
• FlyBaseID: FBgn0035627
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_011612.3
• Gene: ESP1 / 852990
• SGDID: S000003330
• Length: 1630
• Species: Saccharomyces cerevisiae
• Alignment Length: 648
• Identity: 131/648 - (20%)
• Similarity: 237/648 - (36%)
• Gaps: 165/648 - (25%)

  Fly     9 EMLAGFTSS-DVGPEAKEYNLLRADEEYRNG-----------------NVEHSIYYQVKAQFQST 55
            |...|..|| .|.|.....|:|:...::..|                 |:... :.::.|..:..
Yeast   991 ESTLGIPSSLPVIPSTMPNNILKTPSKHSTGLKLCDSPRSSSMTPRGKNIRQK-FDRIAAISKLK 1054

  Fly    56 DLRYLTESAELENQRPTAEELIKSATKLEKKDYKSKKFLQNIIKYLQQMEQEKQPKKPINEIPEY 120
            .::.|.||.:|:.........|.|.:.|      :...|.||.. :...|........:.::|.:
Yeast  1055 QMKELLESLKLDTLDNHELSKISSLSSL------TLTILSNITS-IHNAESSLITNFSLTDLPRH 1112

  Fly   121 LDFLDDVQDPTEGLTRISEKCNSLPQEWCVLQLCKSFNPAT-TYSV-----FNEIIASDGAIYLT 179
            :..|.|     :.|..|.   |...:|:.|..|....|.:| |.|:     ..:::.|:..|.:.
Yeast  1113 MPLLFD-----KVLNNID---NKNYREFRVSSLIAPNNISTITESIRVSAAQKDLMESNLNINVI 1169

  Fly   180 LLRHC------RSSQLGP-------ICLKISNENTANL------FREYS----TLVERFRRVVTV 221
            .:..|      ..|:|.|       :.|.:...|:.:|      |.|.:    :::....:..:|
Yeast  1170 TIDFCPITGNLLLSKLEPRRKRRTHLRLPLIRSNSRDLDEVHLSFPEATKKLLSIINESNQTTSV 1234

  Fly   222 DPLN-MKGKEAKQKYWEELNGFDTFQQKLLADFR-------------DIISPYSF-LFFGKRYDC 271
            :..| :|.:|.::.:|......|...|:||.:..             :::....| .|..|.|:
Yeast  1235 EVTNKIKTREERKSWWTTRYDLDKRMQQLLNNIENSWFNGVQGFFSPEVVDNSLFEKFKDKFYE- 1298

  Fly   272 TVVQKQI--------KATYTRVDD-----FCLLNQWGTHQRVLLSQAASHANRLEIADLKLICYE 323
             ::.:.:        .|.:.:|:|     |..||          .|.....:::|  ||.....:
Yeast  1299 -ILHQNLPSRKLYGNPAMFIKVEDWVIELFLKLN----------PQEIDFLSKME--DLIYFVLD 1350

  Fly   324 LSSNENEIQSAYELLKGLASDWA----EVEE-----RQPLASRR-FPIILVVDERLDHLHWEQLV 378
            :.....| ::||:.:     |::    ::||     |..:.:.. |...|||........||.|.
Yeast  1351 ILLFHGE-ENAYDEI-----DFSMLHVQLEEQIKKYRATMTTNSIFHTFLVVSSSCHLFPWECLS 1409

  Fly   379 TVQEFS--RVKSLHCLWRLFQNH----------KSNIKHGYYTTNIKRGMCVINPDADLVNSGRR 431
            .:::.|  ||.|..||.:|....          :.||.            .::||:.||..:..:
Yeast  1410 FLKDLSITRVPSYVCLNKLLSRFHYQLPLQVTIEDNIS------------MILNPNGDLSRTESK 1462

  Fly   432 LRSFFEYWLS---QWQHLFETVPNEEVMVKQALQADCFVYAGHGSGLQYVNGRIICRARVRSVVF 493
            .:..|:..:.   ..|.:....|.||.::|....::.|||.|||.|.|||..:.|.:....:..|
Yeast  1463 FKGMFQKIIDAKPSSQLVMNEKPEEETLLKMLQNSNLFVYIGHGGGEQYVRSKEIKKCTKIAPSF 1527

  Fly   494 LFGCDSTRM--------LGTGLYSALYGAHDYYHGALCPSIVGTLMPALDGNMDTVSVTILSR 548
            |.||.|..|        .|| :|:.|.|.        ||.::|.|....|.::|..|..:..:
Yeast  1528 LLGCSSAAMKYYGKLEPTGT-IYTYLLGG--------CPMVLGNLWDVTDKDIDKFSEELFEK 1581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sse	NP_523935.1	Peptidase_C50	171..538	CDD:281555	94/450 (21%)
ESP1	NP_011612.3	ESP1	1..1630	CDD:227484	131/648 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346686
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5155
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7216
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003217
OrthoInspector	1	1.000	-	-		oto99902
orthoMCL	1	0.900	-	-		OOG6_103054
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R264
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.710