Protein Alignment Sse and ZK430.5

DIOPT Version :9

• Sequence 1: NP_523935.1
• Gene: Sse / 38640
• FlyBaseID: FBgn0035627
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001364682.1
• Gene: ZK430.5 / 191319
• WormBaseID: WBGene00022741
• Length: 1264
• Species: Caenorhabditis elegans
• Alignment Length: 622
• Identity: 120/622 - (19%)
• Similarity: 221/622 - (35%)
• Gaps: 190/622 - (30%)

  Fly    62 ESAELENQRPTAEELIKSATKLEKKDYKSKKF-------------------LQNIIKYLQQMEQE 107
            :|...||.|.|.:..::....:..::::.:.:                   ..||.....|.||.
 Worm   638 DSQRFENNRLTMQREMQYFAHILYREWRCRMYSYVGKTSKSSWEAAYGWAESTNIGSRNAQQEQL 702

  Fly   108 KQPKKPINEIPEYLDFLDDVQDPTEGLTRISEKCNSLPQEWCVLQLCKSFNPATTYSVFNEIIAS 172
            .:.|..:..||              |:...:....::|.:..::|:               ::|.
 Worm   703 GKCKSGLVTIP--------------GVHHFNSCGQNMPDDMTLIQI---------------VMAD 738

  Fly   173 DGAIYLTLLRHCRSSQLGPICLKISNENTA-NLFREYSTLVERFRRVVTVDPLNMKGKEAKQKY- 235
            |..|||..|...|.    ||.:.:::.:.| .:..:::.|:|..|::|:        ...|.|:
 Worm   739 DKTIYLVKLHADRD----PIIMPLAHYHQAIEVMDKFTYLLEEDRQIVS--------NHEKYKFE 791

  Fly   236 --WEELNGFDTFQQKLLADFRDIISPYSFLFFGKRYDCTVVQKQIKATYTRVDDFCLLNQWGTHQ 298
              |               |.|.|:            ||     |:|.        |:.|.    |
 Worm   792 ECW---------------DRRKIV------------DC-----QMKK--------CVENT----Q 812

  Fly   299 RVLLSQAAS----------HANRLEI------------ADLKLICY------------------E 323
            :..|..|||          :|..|.|            .:.|.:.|                  |
 Worm   813 KHFLGAAASLLLPSGRLGPNATALAIKMYNMAKGGLLPGEAKELVYQSKFIHPKTWKSLVLRYCE 877

  Fly   324 LSSNENEIQSAYELLKGLASDWAEVEERQPLASRRFPIILVVDERLDHLHWEQLVTVQEFSRVK- 387
            :...:|:.:|...||:....:..:.::..| ||.:....||:...|....||:|....:|..|.
 Worm   878 MRGIDNKSKSQLLLLRKDGFNAMKQDQTIP-ASSKIYTHLVICPYLSQFCWERLPIFAKFPYVVR 941

  Fly   388 --SLHCLWRLFQNHKSNIKHGYYTTNIKRGMCVINPDADLVNSGRRLRSFFEYWLSQWQHLFETV 450
              |:|..:....:.::..|.......::....:::||.:|..:.||:..:...:  .|:....:.
 Worm   942 HISIHSAFSQLDDMRNQNKQIPLNIGLENAFYILDPDNNLNGTKRRMLKYINKF--NWEGSVGSA 1004

  Fly   451 PNEEVMVKQALQADCFVYAGHGSGLQYVNGRIICRARVRSVVFLFGCDSTRMLGTGLYSALYGAH 515
            |....:.....:.|.|.|.|||||...|...:|.:....::.||.||:|.|.:..        ||
 Worm  1005 PKLTEVTDALSKRDAFFYFGHGSGSSVVTQSLIRQTTCNAISFLMGCESVRTIPQ--------AH 1061

  Fly   516 DY--------YHGALCPSIVGTLMPALDGNMDTVSVTILSRWLAPGDN--KVIPWTHIDRVPWLK 570
            .:        |..|.|||:||.|.          .|.::::..:.|:|  :.:|.|....:.:.|
 Worm  1062 GFDGTSVIQDYAMAKCPSLVGCLW----------DVQVVAKHTSIGNNGKENLPITTGRMISYSK 1116

  Fly   571 NGIIKGKDETTPTMND---QPNYHLGSLCSILSLVQQ 604
            ...|:   ||.|..::   ..||:  ::.|..||.|:
 Worm  1117 KPKIR---ETEPNSSNLILASNYN--NITSKASLSQE 1148

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sse	NP_523935.1	Peptidase_C50	171..538	CDD:281555	88/421 (21%)
ZK430.5	NP_001364682.1	CHAT	737..1087	CDD:418552	88/426 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167651
Domainoid	1	1.000	61	1.000	Domainoid score	I6929
eggNOG	1	0.900	-	-		E1_COG5155
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7216
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003217
OrthoInspector	1	1.000	-	-		otm14566
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R264
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.810