Protein Alignment Blimp-1 and Prdm5

DIOPT Version :10

• Sequence 1: NP_001261442.1
• Gene: Blimp-1 / 38638
• FlyBaseID: FBgn0035625
• Length: 1216
• Species: Drosophila melanogaster
• Sequence 2: XP_063142792.1
• Gene: Prdm5 / 689788
• RGDID: 1588700
• Length: 630
• Species: Rattus norvegicus
• Alignment Length: 930
• Identity: 191/930 - (20%)
• Similarity: 292/930 - (31%)
• Gaps: 346/930 - (37%)

  Fly   122 LPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNK---ARYFWRVQGT 183
            :|....||||.|..     ..|::::..:.:|.:||||.|  ....|.|.::   .|..|.|:|:
  Rat     6 VPDRFALKSSRVQD-----GMGLYTARRVRKGEKFGPFAG--EKRMPEDLDENMDYRLMWEVRGS 63

  Fly   184 RHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHQENIYFYTTRDILPNE 248
                       |.:..|.||.::...|||:|:|..|.|....||.|.|..|||::....||..:.
  Rat    64 -----------KGEVLYILDATNPRHSNWLRFVHEAPSQERKNLAAIQEGENIFYLAVDDIETDT 117

  Fly   249 ELMVWYCKDFASRLGYDVDPETTIFGACKQAVEAEEEADEEEEEA--EGEDGKPRYSMPAPEIPP 311
            ||::.|                         ::::.||:|||::|  ...:||
  Rat   118 ELLIGY-------------------------LDSDVEAEEEEQQALTMAREGK------------ 145

  Fly   312 DVAVSHITYVMGLHLPVGAGNGPANGSV-AGSVSGATPPPPTATPCCRRSSPPAHVSTTTSTCNA 375
               |.|                 :.|.: |||..........|.|.|..|.|...|.|
  Rat   146 ---VDH-----------------SKGQLAAGSKGHLGCEEDFACPQCESSFPSEEVLT------- 183

  Fly   376 HHPHIQHGRHASVIIGQDRSPMASSDKDTAGSPLSGLDHQMTPQDGSVRSVRSDEGYHSNECHED 440
                 :|                          |..|..:.|             |....:|...
  Rat   184 -----EH--------------------------LQSLHQKPT-------------GEKEFKCENC 204

  Fly   441 GLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPSSSPPAV--VMANTTTNSMISHSSPT 503
            |...|.    .::...:||.|:.::            ....|||.|  .:.|:..:|.:|.|...
  Rat   205 GKKFPV----RQALQRHVLSCAARS------------NLQDSPPRVQCSLCNSLFSSALSFSQHQ 253

  Fly   504 ATPICETDKNEYRKFKVKMPLKYEFKNKTCVKQEPSLKEVDQEMSLPQEEEEDQVMHPEPD---S 565
            ..  |..|            .::..|..:|.|:   ||..|   :|.:..|......|:..   |
  Rat   254 KA--CRGD------------ARFVCKVDSCGKR---LKSKD---ALKRHRENVHTGDPKRKLICS 298

  Fly   566 ICPSTTTHLG--DEHMLMME--------------RERERERERIQEREPSNQQPASSTVIVLEHN 614
            :|....|.|.  .||..:.|              .:.:|......|:.|.|.:..:.:...|:
  Rat   299 VCNRRCTSLSSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHSEKRPYNCEICNKSFKRLD-- 361

  Fly   615 SGGQARTIVPLSKPYYEPDPPGERYMRFGQPSSSILETILTSQHRLEAAAAAANACRQANAATPP 679
            ..|..:.|....|||                                       .|:...
  Rat   362 QVGAHKVIHSEDKPY---------------------------------------QCKLCG----- 382

  Fly   680 PTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQNPEQLSSSAVVVGEQEMTRATMIKGECSP---PP 741
                        |...:.|.......::..:.|.|..                   ||..   .|
  Rat   383 ------------KGFAHRNVYKNHKKTHSEERPFQCD-------------------ECKALFRTP 416

  Fly   742 PSHHHHNVIFSPSRHAAYLGAGEAGGHSPSPGYPGYPHYGAAATSTFHSPPHSSHSPFDRQSNAS 806
            .|...|.:|.:..|                               ||..  |...:.|.|:
  Rat   417 FSLQRHLLIHNSER-------------------------------TFKC--HHCDATFKRK---- 444

  Fly   807 SGAGSATNLHLLQTSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLAS 871
                ...|:|:     |:::          :|....|.          ..|  |.:.::|:.|.|
  Rat   445 ----DTLNVHV-----QVVH----------ERHKKYRC----------ELC--SKAFVTPSVLRS 478

  Fly   872 RGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKH 936
            .        .|...|:....|..|.:.|.....|:||:|:|:||||::|..|.|.|::...|:.|
  Rat   479 H--------KKTHTGEKEKVCPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKNDGLKMH 535

  Fly   937 HLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRP 1001
            ...||.|||:||..|.|.||....|..|.|.|:|:||:.||:|...|:....|..||..|..:||
  Rat   536 IRTHTREKPYQCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLIRHKMTHNPNRP 600

  Fly  1002 YV-CQGCDKKYISASGLRTH 1020
            .. |..|.||:.....|:.|
  Rat   601 MAECHFCHKKFTRNDYLKVH 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Blimp-1	NP_001261442.1	PR-SET_PRDM1	120..262	CDD:380964	42/142 (30%)
		zf-C2HE	<871..912	CDD:465082	10/40 (25%)
		C2H2 Zn finger	892..912	CDD:275368	7/19 (37%)
		zf-H2C2_2	904..929	CDD:463886	13/24 (54%)
		C2H2 Zn finger	920..940	CDD:275368	6/19 (32%)
		SFP1	<938..1020	CDD:227516	33/82 (40%)
		C2H2 Zn finger	948..968	CDD:275368	8/19 (42%)
		C2H2 Zn finger	976..996	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1004..1023	CDD:275368	6/17 (35%)
Prdm5	XP_063142792.1	None