Protein Alignment Blimp-1 and Prdm5

DIOPT Version :9

• Sequence 1: NP_001261442.1
• Gene: Blimp-1 / 38638
• FlyBaseID: FBgn0035625
• Length: 1216
• Species: Drosophila melanogaster
• Sequence 2: XP_038964622.1
• Gene: Prdm5 / 689788
• RGDID: 1588700
• Length: 599
• Species: Rattus norvegicus
• Alignment Length: 947
• Identity: 188/947 - (19%)
• Similarity: 273/947 - (28%)
• Gaps: 411/947 - (43%)

  Fly   122 LPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNK---ARYFWRVQGT 183
            :|....||||.|..     ..|::::..:.:|.:||||.|  ....|.|.::   .|..|.|:|:
  Rat     6 VPDRFALKSSRVQD-----GMGLYTARRVRKGEKFGPFAG--EKRMPEDLDENMDYRLMWEVRGS 63

  Fly   184 RHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHQENIYFYTTRDILPNE 248
                       |.:..|.||.::...|||:|:|..|.|....||.|.|..|||::....||..:.
  Rat    64 -----------KGEVLYILDATNPRHSNWLRFVHEAPSQERKNLAAIQEGENIFYLAVDDIETDT 117

  Fly   249 ELMVWYCKDFASRLGYDVDPETTIFGACKQAVEAEEEADEEEEEA--EGEDGKPRYSMPAPEIPP 311
            ||::.|                         ::::.||:|||::|  ...:||
  Rat   118 ELLIGY-------------------------LDSDVEAEEEEQQALTMAREGK------------ 145

  Fly   312 DVAVSHITYVMGLHLPVGAGNGPANGSV-AGSVSGATPPPPTATPCCRRSSPPAHVST------- 368
               |.|                 :.|.: |||..........|.|.|..|.|...|.|
  Rat   146 ---VDH-----------------SKGQLAAGSKGHLGCEEDFACPQCESSFPSEEVLTEHLQSLH 190

  Fly   369 ---------TTSTCNAHHP-------HIQHGRHASVIIGQDRSPMASSDKDTAGSPLSGLD---- 413
                     ....|....|       |.:  :|.....|..|   .....|:.|..|...|
  Rat   191 QKPTGEKEFKCENCGKKFPVRQALQRHFE--QHQKACRGDAR---FVCKVDSCGKRLKSKDALKR 250

  Fly   414 -----HQMTPQDGSVRSVRSDEGYHSNECHEDGLTPPEDSSDSESEHNYV------LDCSKKAIA 467
                 |...|:...:.||      .:..|         .|..|..||..:      .:|.||.|:
  Rat   251 HRENVHTGDPKRKLICSV------CNRRC---------TSLSSLQEHRKIHEIFDCQECMKKFIS 300

  Fly   468 PKETVIAQAQKPSSSPPAVVMANTTTNSMISHSSPTATPICETDKNEYRKFKVKMPLKYEFKNKT 532
                                 ||.....||:||.                   |.|...|..||
  Rat   301 ---------------------ANQLKRHMITHSE-------------------KRPYNCEICNK- 324

  Fly   533 CVKQEPSLKEVDQEMSLPQEEEEDQVMHPEPDSICPSTTTHLGDEHMLMMERERERERERIQERE 597
                  |.|.:||..:       .:|:|.|
  Rat   325 ------SFKRLDQVGA-------HKVIHSE----------------------------------- 341

  Fly   598 PSNQQPASSTVIVLEHNSGGQARTIVPLSKPYYEPDPPGERYMRFGQPSSSILETILTSQHRLEA 662
                                        .|||
  Rat   342 ----------------------------DKPY--------------------------------- 345

  Fly   663 AAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQNPEQLSSSAVVVGEQEM 727
                  .|:...                 |...:.|.......::..:.|.|..
  Rat   346 ------QCKLCG-----------------KGFAHRNVYKNHKKTHSEERPFQCD----------- 376

  Fly   728 TRATMIKGECSP---PPPSHHHHNVIFSPSRHAAYLGAGEAGGHSPSPGYPGYPHYGAAATSTFH 789
                    ||..   .|.|...|.:|.:..|                               ||.
  Rat   377 --------ECKALFRTPFSLQRHLLIHNSER-------------------------------TFK 402

  Fly   790 SPPHSSHSPFDRQSNASSGAGSATNLHLLQTSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDG 854
            .  |...:.|.|:        ...|:|:     |:::          :|....|.
  Rat   403 C--HHCDATFKRK--------DTLNVHV-----QVVH----------ERHKKYRC---------- 432

  Fly   855 NSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFK 919
            ..|  |.:.::|:.|.|.        .|...|:....|..|.:.|.....|:||:|:|:||||::
  Rat   433 ELC--SKAFVTPSVLRSH--------KKTHTGEKEKVCPYCGQKFASSGTLRVHIRSHTGERPYQ 487

  Fly   920 CNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFT 984
            |..|.|.|::...|:.|...||.|||:||..|.|.||....|..|.|.|:|:||:.||:|...|:
  Rat   488 CPYCEKGFSKNDGLKMHIRTHTREKPYQCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFS 552

  Fly   985 QFVHLKLHKRLHTNDRPYV-CQGCDKKYISASGLRTH 1020
            ....|..||..|..:||.. |..|.||:.....|:.|
  Rat   553 LKKMLIRHKMTHNPNRPMAECHFCHKKFTRNDYLKVH 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Blimp-1	NP_001261442.1	SET	133..260	CDD:214614	37/129 (29%)
		C2H2 Zn finger	892..912	CDD:275368	7/19 (37%)
		zf-H2C2_2	904..929	CDD:290200	13/24 (54%)
		C2H2 Zn finger	920..940	CDD:275368	6/19 (32%)
		zf-H2C2_2	932..957	CDD:290200	12/24 (50%)
		C2H2 Zn finger	948..968	CDD:275368	8/19 (42%)
		zf-H2C2_2	960..985	CDD:290200	11/24 (46%)
		C2H2 Zn finger	976..996	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1004..1023	CDD:275368	6/17 (35%)
Prdm5	XP_038964622.1	PR-SET_PRDM5	2..128	CDD:380967	42/164 (26%)
		C2H2 Zn finger	169..190	CDD:275368	6/20 (30%)
		COG5048	186..590	CDD:227381	125/692 (18%)
		C2H2 Zn finger	201..221	CDD:275368	3/21 (14%)
		C2H2 Zn finger	233..256	CDD:275368	4/22 (18%)
		C2H2 Zn finger	266..286	CDD:275368	7/34 (21%)
		C2H2 Zn finger	291..311	CDD:275368	8/40 (20%)
		C2H2 Zn finger	319..339	CDD:275368	8/33 (24%)
		C2H2 Zn finger	347..367	CDD:275368	3/36 (8%)
		C2H2 Zn finger	375..395	CDD:275368	5/38 (13%)
		C2H2 Zn finger	403..420	CDD:275368	4/26 (15%)
		C2H2 Zn finger	432..452	CDD:275368	6/39 (15%)
		C2H2 Zn finger	460..480	CDD:275368	7/19 (37%)
		C2H2 Zn finger	488..508	CDD:275368	6/19 (32%)
		C2H2 Zn finger	516..536	CDD:275368	8/19 (42%)
		C2H2 Zn finger	544..564	CDD:275368	7/19 (37%)
		C2H2 Zn finger	573..594	CDD:275368	6/17 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910