DRSC/TRiP Functional Genomics Resources

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Protein Alignment Blimp-1 and wor

DIOPT Version :10

Sequence 1:NP_001261442.1 Gene:Blimp-1 / 38638 FlyBaseID:FBgn0035625 Length:1216 Species:Drosophila melanogaster
Sequence 2:NP_476601.1 Gene:wor / 34906 FlyBaseID:FBgn0001983 Length:548 Species:Drosophila melanogaster


Alignment Length:614 Identity:129/614 - (21%)
Similarity:213/614 - (34%) Gaps:177/614 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   593 IQEREPSNQQPASSTVIVLEHNSG----GQARTIVPLSKPYY----EPDP---PGERYMRFGQPS 646
            ::|..|.:.         |.|:.|    ..|...||: :|::    ||:|   |.|...||    
  Fly    18 VEESSPEDH---------LSHDEGPVDLSVASAAVPM-EPHWMAKSEPEPQPVPTELRRRF---- 68

  Fly   647 SSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQN 711
                 ....:|.:.:.|.......|:...|.|...:..|:|.|..: ..||....|.....:...
  Fly    69 -----DAAMNQTKEQLARRIWEETREIARAFPDVFTREEIAKSLAR-LGYGEFELPPEEEVMEPE 127

  Fly   712 PEQLSSSAVVVGEQEM----TR---ATMIKGECSPP---PPSHHHHNVIFSPSRHAAYL---GAG 763
            ||.         ||.:    ||   .|:||.|.|..   |..::::|::.|.:.:...:   ...
  Fly   128 PEP---------EQHLPLRYTRDASPTIIKAEPSDEEQFPLRNYNNNLLKSIAEYEDCMKMQNIK 183

  Fly   764 EAGGHSPSPGYPGYPHYGAAATSTFHSPPHSSHSPFDRQSNASSGAGSATNLHLLQTSTQMLNHP 828
            |.....|||             ..|:.||.....|.|.         |.|...:|..:..:.|  
  Fly   184 EEIPPIPSP-------------QLFYPPPTPLAEPEDL---------SVTQRRVLSENMNLQN-- 224

  Fly   829 LMQPLTPLQRLSPLRISPPSSLSPDG-----------------------NSCPRSGSPLSPNSLA 870
            :.:.|..:|.::|....||..:..|.                       |.|..:.:.|..:. .
  Fly   225 VARALLSMQHMAPQHAPPPIDMEEDQENQDINQLKIKSSNDLYYQCQQCNKCYATYAGLVKHQ-Q 288

  Fly   871 SRGYRSLPY-------------------------------------PLKKKDGKMHYECNVCCKT 898
            :..|.|..|                                     .::|..|...|.|..|.|:
  Fly   289 THAYESTEYKIIRSQPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKS 353

  Fly   899 FGQLSNLKVHLRTH--SGE-----RPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFS 956
            :...|.|..|.:.|  |.|     :.|.|..|.|::..|..|:.|...||  .|.:|.||.|.||
  Fly   354 YSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHT--LPCKCPICGKAFS 416

  Fly   957 STSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHW 1021
            ....|:.|:|.|:|:||::|..|.:.|....:|:.|.:.|::.:.|.|..|.|.:...|.|..|.
  Fly   417 RPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHL 481

  Fly  1022 KTTSCKPNNLEEELAMAAAATSECLDKDHPEPDSREAYEQLTQHMHPAVHPGLRHLSSGGQSPPR 1086
            : :.|     :.|.:...:.:....|:           :||.||:         .:...|.:|.:
  Fly   482 Q-SGC-----QTEQSGGPSGSGGGFDQ-----------QQLQQHL---------QVYEEGHNPHQ 520

  Fly  1087 LIPLGNHMAPQQQSHQQQQQQHQQQGVPP 1115
            |...|:  .......:::..::|.|  ||
  Fly   521 LYYAGS--VGSSNGEEEEGGEYQMQ--PP 545

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Blimp-1NP_001261442.1 PR-SET_PRDM1 120..262 CDD:380964
zf-C2HE <871..912 CDD:465082 12/77 (16%)
C2H2 Zn finger 892..912 CDD:275368 6/19 (32%)
zf-H2C2_2 904..929 CDD:463886 9/31 (29%)
C2H2 Zn finger 920..940 CDD:275368 6/19 (32%)
SFP1 <938..1020 CDD:227516 28/81 (35%)
C2H2 Zn finger 948..968 CDD:275368 9/19 (47%)
C2H2 Zn finger 976..996 CDD:275368 5/19 (26%)
C2H2 Zn finger 1004..1023 CDD:275368 6/18 (33%)
worNP_476601.1 C2H2 Zn finger 270..290 CDD:275368 3/20 (15%)
C2H2 Zn finger 317..334 CDD:275368 0/16 (0%)
zf-C2H2 345..367 CDD:395048 7/21 (33%)
C2H2 Zn finger 347..367 CDD:275368 6/19 (32%)
zf-C2H2 380..402 CDD:395048 7/21 (33%)
C2H2 Zn finger 382..402 CDD:275368 6/19 (32%)
zf-C2H2 406..428 CDD:395048 9/21 (43%)
C2H2 Zn finger 408..428 CDD:275368 9/19 (47%)
zf-C2H2 434..456 CDD:395048 5/21 (24%)
C2H2 Zn finger 436..456 CDD:275368 5/19 (26%)
C2H2 Zn finger 464..481 CDD:275368 5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

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