Protein Alignment Ir64a and Ir8a

DIOPT Version :10

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Alignment Length: 763
• Identity: 146/763 - (19%)
• Similarity: 252/763 - (33%)
• Gaps: 224/763 - (29%)

  Fly   153 RQIAVVDLACGA-----------VSRRFLELASAKMLYSEKFHWLLIEDFAWHGRTQTAEGSGKR 206
            |.:.:.||.||:           |.|..:..|..    |..:...:.:|.     ..||..|...
  Fly   247 RSMPMPDLYCGSGFTMQRAMLLNVLRSLINAAQV----SPGYPLAIYQDC-----NATASSSEVS 302

  Fly   207 DDGEMEEEE--------------PPGQQIQATDDEDLPSIESFLGGMNLYMNTELTLAKRMSEAA 257
            |..|.::..              ||...||......:|.               ||.|..:| |.
  Fly   303 DPLEKDDYNWLDMVHWSNFLAYAPPLPHIQDQFQSPVPG---------------LTFAVNIS-AG 351

  Fly   258 HYTLFDVWNPGLNYGGHVNLTEIGSFTPTEGIQLHTWFRTTSTVRRRMDMQHARVRCMVVVTNKN 322
            :|:           ..|...|::.:::....::|..  .|.|..||...:..|.......:..:.
  Fly   352 YYS-----------SEHEAKTDLAAWSSVGEMRLLN--ETISPARRFFRIGTAESIPWSYLRREE 403

  Fly   323 MTGTLMYYLTHTMSGHIDTMNRFNFNLLMAVRDMFNWTF--VLSRTTSWGYVKN-GRFDGMIGAL 384
            .||.|:    ...|| :.....:..:.::.:....|:.|  |.......|.:.. |.:||::|.|
  Fly   404 GTGELI----RDRSG-LPIWEGYCIDFIIRLSQKLNFEFEIVAPEVGHMGELNELGEWDGVVGDL 463

  Fly   385 IRNETDIGGAPIFYWLERHKWIDVAGRSWSSRPCFI-FRHP-RSTQKDRIVFLQPFTNDVWILIV 447
            :|.|||...|.:..:.||.:.||.....:......| .|.| |.|...:  |:.....:||:.||
  Fly   464 VRGETDFAIAALKMYSEREEVIDFLPPYYEQTGISIAIRKPVRRTSLFK--FMTVLRLEVWLSIV 526

  Fly   448 GCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVS 512
            ...|.|..::||:.    |..|                  |..:..::......|..|
  Fly   527 AALVGTAIMIWFMD----KYSP------------------YSSRNNRQAYPYACREFT------- 562

  Fly   513 KEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQ 577
                                                              ..||..|.:.....|
  Fly   563 --------------------------------------------------LRESFWFALTSFTPQ 577

  Fly   578 GLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVGTLLMEKPKT-IKTLSDLVHSS------LK- 634
            |.|.:...:|||.:|....||...:...::|::...|.:|:.:| :::|..|...|      :|
  Fly   578 GGGEAPKAISGRMLVAAYWLFVVLMLATFTANLAAFLTVERMQTPVQSLEQLARQSRINYTVVKD 642

  Fly   635 -------VGM---EDILYN--RDYFLH-TKDPVSMELYAKKITSVPTTKENEADEDEPVDPNPVS 686
                   |.|   ||.||.  ::..|: :||.....::                 |.|:
  Fly   643 SDTHQYFVNMKFAEDTLYRMWKELALNASKDFKKFRIW-----------------DYPI------ 684

  Fly   687 TDPAKSYRDI---VHSHETGAHAKDNAASNWLDPETGLLRHLGFAF-HVDVAAAYKIIAETFSEQ 747
               .:.|..|   ::|.:..|.||:..|:  :|..    .:..:|| |......|:|...
  Fly   685 ---KEQYGHILLAINSSQPVADAKEGFAN--VDAH----ENADYAFIHDSAEIKYEITRN----- 735

  Fly   748 DICDLTEV-SMFPPQKTVSIMQKNSPMRKVISYGLRRVTETGIL-TYHFNVWH-SRKPPCVKKIE 809
              |:|||| .:|..|.....:|:.|.:...:||.:..:.:.... ......|: |..|.|  .:.
  Fly   736 --CNLTEVGEVFAEQPYAVAVQQGSHLGDELSYAILELQKDRFFEELKAKYWNQSNLPNC--PLS 796

  Fly   810 TSDLHVDMDTVSSALLILLFSYAITLMILGTEIL-YSKWHNRIQLKWV 856
            .....:.::::....:..||...:.:|.||.|:| |.|..|.:::..|
  Fly   797 EDQEGITLESLGGVFIATLFGLVLAMMTLGMEVLYYKKKQNALEITQV 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	32/118 (27%)
		Lig_chan	563..828	CDD:459656	59/292 (20%)
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	100/527 (19%)