Protein Alignment Gen and RAD27

DIOPT Version :10

• Sequence 1: NP_647943.2
• Gene: Gen / 38594
• FlyBaseID: FBgn0263831
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_012809.1
• Gene: RAD27 / 853747
• SGDID: S000001596
• Length: 382
• Species: Saccharomyces cerevisiae
• Alignment Length: 522
• Identity: 110/522 - (21%)
• Similarity: 183/522 - (35%)
• Gaps: 173/522 - (33%)

  Fly     1 MGVKELWGVLTPH----CERKPINELRGKKVAIDLAGWVCESLNVVDYFVHPRH----------- 50
            ||:|.|..:::.|    ..:..|....|:|||||      .|:::..:.:..|.
Yeast     1 MGIKGLNAIISEHVPSAIRKSDIKSFFGRKVAID------ASMSLYQFLIAVRQQDGGQLTNEAG 59

  Fly    51 ----HLKNLFFRTCYLIWEQVTPVFVLEGVAPKLKSQVIAKRNELQFRGVKPKNSPECTQSQPSK 111
                ||..:|:||..:|...:.|.:|.:|..|.|||..:.||:..:....| |.:...|:.:..|
Yeast    60 ETTSHLMGMFYRTLRMIDNGIKPCYVFDGKPPDLKSHELTKRSSRRVETEK-KLAEATTELEKMK 123

  Fly   112 GDKGRSRFNHVLK----QCETLLLSMGIQCVQGPGEAEAYCAFLNKHGLVDGVISQDSDCFAYGA 172
            .::   |...|.|    :.:.||..|||..:..|.||||.||.|.|.|.|....|:|.|...|..
Yeast   124 QER---RLVKVSKEHNEEAQKLLGLMGIPYIIAPTEAEAQCAELAKKGKVYAAASEDMDTLCYRT 185

  Fly   173 VRVYRNFSVSTQGAQAAAGGAVDIYDMREITSRMDFGQQKIIVMALLCGCDYCPDGIGGIGKDGV 237
            ..:.|:.:.|     .|....:...|...:...:|...::.:.:.::.||||| :.|.|:|....
Yeast   186 PFLLRHLTFS-----EAKKEPIHEIDTELVLRGLDLTIEQFVDLCIMLGCDYC-ESIRGVGPVTA 244

  Fly   238 LKLFNKYKETEILDRMRSWRGETDKYNALEIRVDDKSICSNCGHIGKTQSHTKSGCSVCRTHKGC 302
            |||...:                                   |.|.|.....:||.|
Yeast   245 LKLIKTH-----------------------------------GSIEKIVEFIESGES-------- 266

  Fly   303 DESLWKEQRLSIKSELTLRRKALLSPDFPNEEIIAEFLSEPDTIP--NLNLNWRQPNLVKFIKQI 365
            :.:.||                 :..|:|.::....|| :|:.|.  .:||.|..|...:.|
Yeast   267 NNTKWK-----------------IPEDWPYKQARMLFL-DPEVIDGNEINLKWSPPKEKELI--- 310

  Fly   366 GHLLQWPEIYCFQKFFPILTRWQVQQSKQEKILIQPHEIIKKRTVKGVPSLELRWHDPSGIFKGL 430
                   |..|..|.|.                       ::|...|:..|:      .|:..|:
Yeast   311 -------EYLCDDKKFS-----------------------EERVKSGISRLK------KGLKSGI 339

  Fly   431 IPDKQIAEYEAEHPKGIEELYYTIEPLDMLETAYPDLVAAFLKSKEK--PAKKTTRKKKTASEEE 493
                          :|..:.::.:.|                |:||:  .|.|..::.|..::.:
Yeast   340 --------------QGRLDGFFQVVP----------------KTKEQLAAAAKRAQENKKLNKNK 374

  Fly   494 NK 495
            ||
Yeast   375 NK 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gen	NP_647943.2	PIN_GEN1	2..207	CDD:350217	59/227 (26%)
		H3TH_GEN1	210..342	CDD:188625	23/131 (18%)
		Chromo_2	400..473	CDD:465841	7/72 (10%)
RAD27	NP_012809.1	PIN_SF	1..364	CDD:475124	107/508 (21%)