Protein Alignment Gen and Fen1

DIOPT Version :10

• Sequence 1: NP_647943.2
• Gene: Gen / 38594
• FlyBaseID: FBgn0263831
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_523765.1
• Gene: Fen1 / 36887
• FlyBaseID: FBgn0025832
• Length: 385
• Species: Drosophila melanogaster
• Alignment Length: 527
• Identity: 111/527 - (21%)
• Similarity: 192/527 - (36%)
• Gaps: 174/527 - (33%)

  Fly     1 MGVKELWGVLTPHCERKPINELR---GKKVAIDLAGWVC----------ESLNVVDYFVHPRHHL 52
            :|:.:|...|.|...|:  :|::   |:|||||.:  :|          |...:......|..||
  Fly     4 LGLSKLIADLAPQAIRE--SEMKHFFGRKVAIDAS--MCLYQFLIAVRSEGAQLATVNGDPTSHL 64

  Fly    53 KNLFFRTCYLIWEQVTPVFVLEGVAPKLKSQVIAKRNELQFRGVKPKNSPECTQSQPSKG-DKGR 116
            ..:|:||..|:...:.||:|.:|..|.|||..:|||.|      :.:.:.:..::....| |.|.
  Fly    65 MGMFYRTIRLLDNGIKPVYVFDGKPPDLKSGELAKRAE------RREEAEKALKAATDAGDDAGI 123

  Fly   117 SRFNHVL--------KQCETLLLSMGIQCVQGPGEAEAYCAFLNKHGLVDGVISQDSDCFAYGAV 173
            .:||..|        |:.:.||..||:..|..|.||||.||.|.|.|.|....::|.|...:|:.
  Fly   124 EKFNRRLVRVTKEHAKEAKELLTLMGVPYVDAPCEAEAQCAALVKAGKVYATATEDMDALTFGST 188

  Fly   174 RVYRNFSVSTQGAQAAAGGAVDIYDMREITSRMDFGQQKIIVMALLCGCDYCPDGIGGIGKDGVL 238
            ::.|..:.|     .|....|..:...::...:....::.|.:.:|.||||| :.|.|||....:
  Fly   189 KLLRYLTYS-----EARKMPVKEFSYDKLLEGLAINNREFIDLCILLGCDYC-ESIKGIGPKRAI 247

  Fly   239 KLFNKYKETE-ILDRMRSWRGETDKYNALEIRVDDKSICSNCGHIGKTQSHTKSGCSVCRTHKGC 302
            :|.|.|::.| |||.:     ::.||..
  Fly   248 ELINTYRDIETILDNL-----DSSKYTV------------------------------------- 270

  Fly   303 DESLWKEQRLSIKSELTLRRKALLSPDFPNEEIIAEFLSEPDT--IPNLNLNWRQPN---LVKFI 362
                                     |:..|.::..|...||:.  ..:::|.|.:|:   ||||:
  Fly   271 -------------------------PENWNYKVARELFIEPEVADADSIDLKWVEPDEEGLVKFL 310

  Fly   363 KQIGHLLQWPEIYCFQKFFPILTRWQVQQSKQEKILIQPHEIIKKRTVKGVPSLELRWHDPSGIF 427
                         |..:           |..:|::.....:::|.:
  Fly   311 -------------CGDR-----------QFNEERVRNGAKKLMKSK------------------- 332

  Fly   428 KGLIPDKQIAEYEAEHPKGIEELYYTIEPLDMLETAYPDLVAAFLKSKEKPAKKTTRKKKTASEE 492
                        :|:....::..:.|:       .:.|:...| .|.|.:.|||:...||..:..
  Fly   333 ------------QAQTQVRLDSFFKTL-------PSTPNATNA-AKRKAEEAKKSANNKKAKTSG 377

  Fly   493 ENKENEP 499
            ..:...|
  Fly   378 GGRGRRP 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gen	NP_647943.2	PIN_GEN1	2..207	CDD:350217	63/226 (28%)
		H3TH_GEN1	210..342	CDD:188625	23/132 (17%)
		Chromo_2	400..473	CDD:465841	5/72 (7%)
Fen1	NP_523765.1	PTZ00217	1..363	CDD:240317	105/504 (21%)