Protein Alignment Tie and Sdr

DIOPT Version :10

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_650408.1
• Gene: Sdr / 41809
• FlyBaseID: FBgn0038279
• Length: 868
• Species: Drosophila melanogaster
• Alignment Length: 315
• Identity: 56/315 - (17%)
• Similarity: 97/315 - (30%)
• Gaps: 115/315 - (36%)

  Fly   418 YKYHMRERGLVPTAAPPPAAPPAPPVSRTRYVGSGRPTAGLSDSIQDLKQTESEVAKPVVRRVVQ 482
            |.||.:|               ||..:.|.|  .||...|..:.:.|:...:|.      |.|:.
  Fly   520 YSYHYKE---------------APVQNVTMY--DGRHGCGHDNWLMDVVPNQSR------RHVIS 561

  Fly   483 KVSPSSSTPLIITVLSAEE-------ETTVGQTEALPTDESTTTTSTTTTTEKPSTTTSTSTTTT 540
            .:.|.:.....:..|:..|       .:.:|..:.||              ::||
  Fly   562 GLKPYTQYAYFVKTLTRTEYHIQIDAYSKIGYFQTLP--------------DRPS---------- 602

  Fly   541 TPVPSTSKRTTTNAPLSTTNTPTTTTSSTTPSTTTTSSTSTTVIPTTTKANSIIE-KDKELIRAL 604
             ||......:..::.:.....|....:....:...|:.          |.|:..| |||..:
  Fly   603 -PVLRIYGSSEISSQILLHWWPPRRPNGVIKNYFVTAE----------KYNATKEAKDKNYV--- 653

  Fly   605 GPALTREINIDDANNLIVFCNNTSDC---GVTP-RTQTQPSHT----------TDSSP------- 648
                  .:.:::|.::        ||   ||.| .:..||...          .|:.|
  Fly   654 ------NVELENAKDI--------DCECAGVLPYYSGPQPDDEDYYNKEQITYEDALPNLIYVSR 704

  Fly   649 ----------KILRTTVLTSIRSTVHP-RPTSTSTTTSTTTTAPPAVTAPSNEVY 692
                      |::....|.||:....| ||.:|:...:..|.|...:.|.:.|.|
  Fly   705 NHDYRRKEFEKVINYEHLLSIKKDEEPTRPPTTTPAPTNATLAKERLAAINYENY 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581
Sdr	NP_650408.1	Recep_L_domain	58..173	CDD:460032
		Furin-like	210..332	CDD:395614
		Recep_L_domain	347..461	CDD:460032
		FN3	491..578	CDD:214495	17/80 (21%)