Protein Alignment Tie and tor

DIOPT Version :10

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Alignment Length: 667
• Identity: 133/667 - (19%)
• Similarity: 211/667 - (31%)
• Gaps: 320/667 - (47%)

  Fly   682 PAVTAPSNEVYIGIVESSSSASPADISSTVIANERDLNMEMRRMNLVTLVLVAVGVIPLAAIILY 746
            |.:|...:...:.:|  :.||...::|...: ::....:.:...|:|.|||..  ::|:..|::.
  Fly   355 PKITVLGSHFEVHLV--AQSAGGKNVSGLTL-DKVHRGVLLSEGNMVKLVLFI--IVPICCILML 414

  Fly   747 LVRNFVIRRRAKQSEVFDVCITDQQPISPVKKVDSKYQVDDDEDEVDHQHHQHMQHHQNHQNHQN 811
            ....|..|.|   |||
  Fly   415 CSLTFCRRNR---SEV------------------------------------------------- 427

  Fly   812 HQHHQAMPMSQASQRDANHNRYGNNDDKTSLASEFH-------------------------DFER 851
                      ||.|.||          |.:.|||||                         :.|.
  Fly   428 ----------QALQMDA----------KDAKASEFHLSLMDSSGLLVTLSANESLEVMDELEVEP 472

  Fly   852 SNIRLKSLLGEGNFGQVWKAEADDLSGHFGATRIVAVKTIRACSAQVSLKDEAN----------- 905
            .::.|:.:||||.||.|.:       |.: ..|.||||.         ||||.|
  Fly   473 HSVLLQDVLGEGAFGLVRR-------GVY-KKRQVAVKL---------LKDEPNDEDVYAFKCEI 520

  Fly   906 -IMRKLGSHQNVVTLLGACVE-SEPHMLIMEYAMRGRLLSLLR---------------------- 946
             :::.:|.|.|:|.::|.... |...||::||...|.|.:.||
  Fly   521 QMLKAVGKHPNIVGIVGYSTRFSNQMMLLIEYCSLGSLQNFLREEWKFRQEQNAIGLKKNLEQNV 585

  Fly   947 --------------------------------------AARSATNIL------------------ 955
                                                  ::|..|..|
  Fly   586 DNRRFNRLPRNSIHDRIEDINNSMLSTVEEESESDQTHSSRCETYTLTRITNAADNKGYGLEDIE 650

  Fly   956 ---------PASVPGGRSLAPLSPR---------------------------------------- 971
                     .|..|..|....|.|:
  Fly   651 NIGGSYIPKTAEAPKDRPKRKLKPQPKKDSKQDFKSDNKKRIFENKEYFDCLDSSDTKPRIPLKY 715

  Fly   972 -TLAGFALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAERMRKEQEKNAA 1035
             .|...|..:|.|||::|..::|||||||||||:..:...||.|||:|.|:
  Fly   716 ADLLDIAQQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIKIADFGLSRDV-------------- 766

  Fly  1036 NDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHALPIRW 1100
                                  :.::.:.:..|.|                        .|||:|
  Fly   767 ----------------------YHENVYRKSGGSG------------------------KLPIKW 785

  Fly  1101 MAPESLQYHMFTTETDIWAFGIVLWEIATLGSTPYSQLTGREVIRRVPQGLRPDLPKESRHEFYN 1165
            :|.|||.:.::|:::|:|:||::|:||.|||..||..::..::::.:.||.|...|:....|.::
  Fly   786 LALESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFS 850

  Fly  1166 LMSRCWHKEPHMRPSFA 1182
            ||..||...|..||:|:
  Fly   851 LMESCWSSVPSHRPTFS 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	102/470 (22%)
tor	NP_476762.1	PTKc	479..873	CDD:270623	101/466 (22%)