DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tie and Tek

DIOPT Version :10

Sequence 1:NP_523928.1 Gene:Tie / 38559 FlyBaseID:FBgn0014073 Length:1233 Species:Drosophila melanogaster
Sequence 2:NP_038718.2 Gene:Tek / 21687 MGIID:98664 Length:1123 Species:Mus musculus


Alignment Length:78 Identity:16/78 - (20%)
Similarity:34/78 - (43%) Gaps:21/78 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   153 PATI----NATRFGNNRVNQDKSCEAENEKKKLTSVSSRERSTIATPSSSSSSPSVQVRGR---- 209
            |||:    ..:..|:::.:.....||:|.:   .|.:.|::|....|:         :||:    
Mouse    35 PATLVIYNEPSASGDDKQSTGHQTEAQNAQ---LSPAQRKQSVYTPPT---------MRGKEHYS 87

  Fly   210 -SRKRRPRALQPS 221
             |::....:.||:
Mouse    88 DSQQEDRESHQPT 100

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TieNP_523928.1 TyrKc 854..1183 CDD:197581
TekNP_038718.2 Ig_Tie2_1 24..118 CDD:463089 16/78 (21%)
EGF_Lam 230..275 CDD:238012
IgI_Tie2 348..439 CDD:409556
Ig strand A 348..352 CDD:409556
Ig strand A' 358..362 CDD:409556
Ig strand B 365..374 CDD:409556
Ig strand C 382..387 CDD:409556
Ig strand C' 391..393 CDD:409556
Ig strand D 397..401 CDD:409556
Ig strand E 404..412 CDD:409556
Ig strand F 420..428 CDD:409556
Ig strand G 431..439 CDD:409556
fn3 445..516 CDD:394996
fn3 542..625 CDD:394996
FN3 638..730 CDD:238020
PTKc_Tie2 815..1117 CDD:133219
Blue background indicates that the domain is not in the aligned region.

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