Protein Alignment Tie and zig-13

DIOPT Version :10

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_497161.1
• Gene: zig-13 / 188571
• WormBaseID: WBGene00020546
• Length: 352
• Species: Caenorhabditis elegans
• Alignment Length: 276
• Identity: 59/276 - (21%)
• Similarity: 82/276 - (29%)
• Gaps: 101/276 - (36%)

  Fly  1017 MSIDLDAERMRKEQEKNAANDLMRHNAHKFKFDFGSRYILQHWQHTFGQG--------------- 1066
            :||.:..|....|.........:|.|..:...|.|          ||..|
 Worm    53 LSISIPPETAFLEYRTKKTGSFVRINYQRAISDDG----------TFDSGVFYNVSLTEDIEFLC 107

  Fly  1067 --QGQGHCSKDQPHGE----------------KKSHHGHDTIGKRHALP---IRWMAPESLQ--- 1107
              :||||.|....|..                :||.:..||:....|:|   |.|.....|:
 Worm   108 WTRGQGHPSFKHIHVADGPSKAFYNVGGAPRFQKSVYEQDTVNLFCAIPHSAINWKVSWRLENSN 172

  Fly  1108 ----------------YHMFTTETDIWAFGIVLWEIATLGSTPYSQLTGREVIRRVPQGLRPDLP 1156
                            ||: ||..:|...|:....|.........||. ..||:..|...||:..
 Worm   173 STSDLSVTTLIDGNSKYHV-TTVKNITKSGVYTCVIEADKFKERRQLL-ETVIKVKPASTRPEPI 235

  Fly  1157 KESRHEFYNLMS------RCWHKEPHMRPSFAQSRLEITRSLHKWVDDDSAASDYMDVSGFSEDL 1215
            |.|:....|..|      :| :...|..|.::            ||.|:|:.|...    .|||
 Worm   236 KSSKMAIPNCKSSIEIEIQC-NITGHPLPEYS------------WVTDESSGSTLT----ISED- 282

  Fly  1216 EHGVVYFNHRISEFEC 1231
             .||         |:|
 Worm   283 -SGV---------FQC 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	47/226 (21%)
zig-13	NP_497161.1	Ig	227..301	CDD:472250	22/90 (24%)
		Ig strand B	251..255	CDD:409442	0/3 (0%)
		Ig strand C	264..268	CDD:409442	0/15 (0%)
		Ig strand E	276..279	CDD:409442	0/6 (0%)
		Ig strand F	285..290	CDD:409442	3/13 (23%)