Protein Alignment Tie and R09D1.12

DIOPT Version :10

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_496025.2
• Gene: R09D1.12 / 174501
• WormBaseID: WBGene00011168
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 382
• Identity: 102/382 - (26%)
• Similarity: 151/382 - (39%)
• Gaps: 129/382 - (33%)

  Fly   860 LGEGNFGQVWKAEADDLSGHFGATRIVAVKTIRACSAQVSLK---------------DEANIMRK 909
            ||:|.||.:.|          |...:...||.......|::|               ||..:|..
 Worm   132 LGKGKFGIINK----------GLLTLRICKTNEVVQVNVAVKKMVDPTDEKQDKLIYDEIKLMCA 186

  Fly   910 LGSHQNVVTLLGACVESEP------HMLIMEYAMRGRLLSLLR----------AARSATNILPAS 958
            :|.|.||:.::||..:.|.      :..:.|:...|.|.|:||          .:|..|
 Worm   187 IGKHPNVLAIVGAITKKEKVSGREYNQAVSEFIEGGDLRSVLRNSPYTFQDEITSRERT------ 245

  Fly   959 VPGGRSL-----APLSPRTLAGFALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMS 1018
              ||:::     ..:|...|..||..||.||||:|....||||||.|||.:..|.:.:|.|||
 Worm   246 --GGQNVDAEVFDTISTSDLFSFAYQIANGMEYLASLPCVHRDLALRNVFVKKNKIIRIGDFG-- 306

  Fly  1019 IDLDAERMRKEQEKNAANDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKS 1083
                               |.|||..|   |:   |.:::              |.:.|
 Worm   307 -------------------LARHNGDK---DY---YKVKY--------------SPETP------ 326

  Fly  1084 HHGHDTIGKRHALPIRWMAPESL-QYHMFTTETDIWAFGIVLWEIATLGSTPYSQLTGRE----- 1142
                        |||.|:|||.. ....||..||:|::|:.|:|:.:||::||.:    |
 Worm   327 ------------LPIFWLAPECFDDGTSFTEMTDVWSYGVCLFELFSLGASPYLE----EFQNFF 375

  Fly  1143 -----VIRRVPQGLRPDLPKESRHEFYNLMSRCWHKEPHMRPSFAQSRLEITRSLHK 1194
                 |:..:..|.|...||..|.:.||.|..||:.:...||.|.:.: |..::|.|
 Worm   376 DPIYYVVAFLESGKRLSSPKYCRSDIYNFMLECWNSDAKQRPRFTKCK-EFFKNLIK 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	99/369 (27%)
R09D1.12	NP_496025.2	TyrKc	127..426	CDD:197581	100/375 (27%)