DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1316 and Spx

DIOPT Version :9

Sequence 1:	NP_647887.1	Gene:	CG1316 / 38526	FlyBaseID:	FBgn0035526	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_511058.1	Gene:	Spx / 31558	FlyBaseID:	FBgn0015818	Length:	347	Species:	Drosophila melanogaster

Alignment Length:	149	Identity:	37/149 - (24%)
Similarity:	64/149 - (42%)	Gaps:	19/149 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 EAFSPYGEIEDIWVVKDKHTQENKGIAYVKFSKTSDAAKAQEEMNG-KTIGKMDRTLKVLV-AAN 107
            |.|...|.:.::.:.||:.||.::|..:|:|....||....:.||. |..||..|..|... ..|
  Fly    31 ELFVQAGPVVNVHMPKDRVTQMHQGYGFVEFLSEEDADYGIKIMNMIKLYGKPIRVNKASAHQKN 95

  Fly   108 RNQGSNKSENEQEKYVRLFIVIPKTATEED---IREEFSQWGDV-ESVTIVKEKNNGNPKGFGYV 168
            .:.|:|             |.|.....|.|   :.:.||.:|.: ::..|:::...|..|.|.::
  Fly    96 LDVGAN-------------IFIGNLDVEVDEKLLYDTFSAFGVILQTPKIMRDPETGKSKSFAFI 147

  Fly   169 RFTKFYYAAVAFENCSAKY 187
            .|..|..:..|.:..:.:|
  Fly   148 NFASFEASDAAMDAMNGQY 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1316	NP_647887.1	RRM1_RBM45	25..105	CDD:240812	19/61 (31%)
		RRM2_RBM45	122..195	CDD:240813	15/70 (21%)
		RRM3_RBM45	267..339	CDD:240814
		RRM4_RBM45	383..449	CDD:240815
Spx	NP_511058.1	RRM1_SF3B4	15..88	CDD:240780	18/56 (32%)
Spx	NP_511058.1	RRM2_SF3B4	99..181	CDD:240781	17/81 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930