DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1273 and Fndc1

DIOPT Version :9

Sequence 1:	NP_647883.1	Gene:	CG1273 / 38522	FlyBaseID:	FBgn0035522	Length:	1168	Species:	Drosophila melanogaster
Sequence 2:	XP_006523412.1	Gene:	Fndc1 / 68655	MGIID:	1915905	Length:	1833	Species:	Mus musculus

Alignment Length:	532	Identity:	119/532 - (22%)
Similarity:	179/532 - (33%)	Gaps:	198/532 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 QNILSVEEYIKESLF------LETSAAK---------SLYRSLRLDTESVEIKRIMDEQVVRSAA 263
            |::.:.||...|.:.      |.||..|         :.|....||.:...|.:::.|:
Mouse  1117 QSVFTEEEEENEGILKGKEDSLSTSVKKWPSSSSPRNNKYADRNLDRDKAAIGQLVQEE------ 1175

  Fly   264 ILKEAQTVPTSQTQLEKRLMKKGSTPATPPVHPKPNPNTTPKPKNPLLRSHSAD---------EE 319
                 .::|..:            :|.:||:  ..:|.|..:|:||:..|.||.         ..
Mouse  1176 -----DSIPGRR------------SPGSPPI--ASHPPTWYQPRNPVTASPSASTHSWPRYTTRA 1221

  Fly   320 PDIDVENAPVI------QGSFEGSFEITKTDADIARKKTPP---TRAYQAASS---TLPPKAIAV 372
            |.......|::      |..|.         ..::|:..|.   |..|...::   .:||.:|..
Mouse  1222 PSTYSSTTPMLSLRQRMQRRFR---------TPVSRQPPPRPVLTSGYNGRANVGENIPPGSIGK 1277

  Fly   373 -------------------------------------TPFSLRVKPKKPSIEKL---TTVLPQQL 397
                                                 .|..:|:.....:|..|   ..|.|..|
Mouse  1278 PNGQRIINGPQGTKWVVDLDRGLVLNAEGRYLQDSHGNPLRVRLGGDGRTIVDLGGTPMVSPDGL 1342

  Fly   398 PT------GGPISSTR---------------ATTKATKATTTTTKRTTTSTTRKTTTTTTPKPTT 441
            |.      |.|::|.:               ...|.|..:.|||...||:||...||||.| |||
Mouse  1343 PLFGQGRHGKPVASAQDKPILSLGGKPLVGLEVIKTTTYSPTTTMLPTTTTTTVLTTTTRP-PTT 1406

  Fly   442 TTTTTEATTTTTTSTTTTTPPLPPSTTRATTTSTNTFTYPSVNTPPPN-QGGSLPKLD--ANLFT 503
            |||||..|||..|:||..    |.:|.|||..:|.|.|.|...||.|. ..|:|...|  .||
Mouse  1407 TTTTTRRTTTRRTTTTRH----PTTTIRATRRTTTTTTTPEPTTPSPTCPPGTLEHQDEAGNL-- 1465

  Fly   504 TFPILDTQPWRPMHREVPELLP------------GPPP-----------AF-----PTKTLPGGT 540
               |:.:       ..:||..|            .||.           .|     ||.|:|..|
Mouse  1466 ---IMGS-------NGIPECYPEEDDFSGLETDTAPPTEEDYVVYDDDYGFETTRPPTSTMPSTT 1520

  Fly   541 TPTVNHIPQRRI------DEFEL-----------PFIADNPTPPTAAVAPVTVDPYSLGFLNPGL 588
            ..|...||::..      :||:|           .:::.:||.|.:...  .:|.:.:..|:..:
Mouse  1521 AATPKVIPEQGTVSSFPEEEFDLAGKRRFVAPYVTYLSKDPTAPCSLTD--ALDHFQVESLDELI 1583

  Fly   589 RVQEPKPNLGPQ 600
            .....|.:|.||
Mouse  1584 PNDLTKSDLPPQ 1595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1273	NP_647883.1	None
Fndc1	XP_006523412.1	FN3	37..117	CDD:214495
		FN3	155..238	CDD:214495
		FN3	258..351	CDD:238020
		FN3	359..449	CDD:238020
		PHA03247	<636..1209	CDD:223021	23/116 (20%)
		FN3	1597..1688	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23197
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100